FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004386902> ?p ?o ?g. }

• W2004386902 endingPage "414" @default.
• W2004386902 startingPage "405" @default.
• W2004386902 abstract "Background Glomerular filtration rate estimation equations use demographic variables to account for predicted differences in creatinine generation rate. In contrast, assessment of albuminuria from urine albumin-creatinine ratio (ACR) does not account for these demographic variables, potentially distorting albuminuria prevalence estimates and clinical decision making. Study Design Polynomial regression was used to derive an age-, sex-, and race-based equation for estimation of urine creatinine excretion rate, suitable for use in automated estimated albumin excretion rate (eAER) reporting. Setting & Participants The MDRD (Modification of Diet in Renal Disease) Study cohort (N = 1,693) was used for equation derivation. Validation populations were the CRIC (Chronic Renal Insufficiency Cohort; N = 3,645) and the DCCT (Diabetes Control and Complications Trial; N = 1,179). Index Test eAER, calculated by multiplying ACR by estimated creatinine excretion rate, and ACR. Reference Test Measured albumin excretion rate (mAER) from timed 24-hour urine collection. Results eAER estimated mAER more accurately than ACR; the percentages of CRIC participants with eAER within 15% and 30% of mAER were 33% and 60%, respectively, versus 24% and 39% for ACR. Equivalent proportions in DCCT were 52% and 86% versus 15% and 38%. The median bias of ACR was −20.1% and −37.5% in CRIC and DCCT, respectively, whereas that of eAER was +3.8% and −9.7%. Performance of eAER also was more consistent across age and sex categories than ACR. Limitations Single timed urine specimens used for mAER, ACR, and eAER. Conclusions Automated eAER reporting potentially is a useful approach to improve the accuracy and consistency of clinical albuminuria assessment. Glomerular filtration rate estimation equations use demographic variables to account for predicted differences in creatinine generation rate. In contrast, assessment of albuminuria from urine albumin-creatinine ratio (ACR) does not account for these demographic variables, potentially distorting albuminuria prevalence estimates and clinical decision making. Polynomial regression was used to derive an age-, sex-, and race-based equation for estimation of urine creatinine excretion rate, suitable for use in automated estimated albumin excretion rate (eAER) reporting. The MDRD (Modification of Diet in Renal Disease) Study cohort (N = 1,693) was used for equation derivation. Validation populations were the CRIC (Chronic Renal Insufficiency Cohort; N = 3,645) and the DCCT (Diabetes Control and Complications Trial; N = 1,179). eAER, calculated by multiplying ACR by estimated creatinine excretion rate, and ACR. Measured albumin excretion rate (mAER) from timed 24-hour urine collection. eAER estimated mAER more accurately than ACR; the percentages of CRIC participants with eAER within 15% and 30% of mAER were 33% and 60%, respectively, versus 24% and 39% for ACR. Equivalent proportions in DCCT were 52% and 86% versus 15% and 38%. The median bias of ACR was −20.1% and −37.5% in CRIC and DCCT, respectively, whereas that of eAER was +3.8% and −9.7%. Performance of eAER also was more consistent across age and sex categories than ACR. Single timed urine specimens used for mAER, ACR, and eAER. Automated eAER reporting potentially is a useful approach to improve the accuracy and consistency of clinical albuminuria assessment." @default.
• W2004386902 created "2016-06-24" @default.
• W2004386902 creator A5007186830 @default.
• W2004386902 creator A5015440553 @default.
• W2004386902 creator A5018294657 @default.
• W2004386902 creator A5019401203 @default.
• W2004386902 creator A5032566816 @default.
• W2004386902 date "2014-03-01" @default.
• W2004386902 modified "2023-10-17" @default.
• W2004386902 title "Estimated Albumin Excretion Rate Versus Urine Albumin-Creatinine Ratio for the Estimation of Measured Albumin Excretion Rate: Derivation and Validation of an Estimated Albumin Excretion Rate Equation" @default.
• W2004386902 cites W1550111394 @default.
• W2004386902 cites W1956069018 @default.
• W2004386902 cites W1965538252 @default.
• W2004386902 cites W1966337012 @default.
• W2004386902 cites W2005064880 @default.
• W2004386902 cites W2005815716 @default.
• W2004386902 cites W2024256372 @default.
• W2004386902 cites W2036943054 @default.
• W2004386902 cites W2037789405 @default.
• W2004386902 cites W2039408552 @default.
• W2004386902 cites W2043470966 @default.
• W2004386902 cites W2045516356 @default.
• W2004386902 cites W2046652195 @default.
• W2004386902 cites W2047390341 @default.
• W2004386902 cites W2055864845 @default.
• W2004386902 cites W2063284508 @default.
• W2004386902 cites W2075391935 @default.
• W2004386902 cites W2087580623 @default.
• W2004386902 cites W2096592656 @default.
• W2004386902 cites W2099628040 @default.
• W2004386902 cites W2101886574 @default.
• W2004386902 cites W2103561970 @default.
• W2004386902 cites W2109793524 @default.
• W2004386902 cites W2114019720 @default.
• W2004386902 cites W2115951150 @default.
• W2004386902 cites W2116888154 @default.
• W2004386902 cites W2118112768 @default.
• W2004386902 cites W2123991466 @default.
• W2004386902 cites W2128867475 @default.
• W2004386902 cites W2134270369 @default.
• W2004386902 cites W2148983669 @default.
• W2004386902 cites W2155965977 @default.
• W2004386902 cites W2167551217 @default.
• W2004386902 cites W2170635160 @default.
• W2004386902 cites W2171699929 @default.
• W2004386902 cites W2323304773 @default.
• W2004386902 cites W2467227824 @default.
• W2004386902 cites W2769264260 @default.
• W2004386902 cites W2098882075 @default.
• W2004386902 doi "https://doi.org/10.1053/j.ajkd.2013.08.009" @default.
• W2004386902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24084157" @default.
• W2004386902 hasPublicationYear "2014" @default.
• W2004386902 type Work @default.
• W2004386902 sameAs 2004386902 @default.
• W2004386902 citedByCount "38" @default.
• W2004386902 countsByYear W20043869022014 @default.
• W2004386902 countsByYear W20043869022015 @default.
• W2004386902 countsByYear W20043869022016 @default.
• W2004386902 countsByYear W20043869022017 @default.
• W2004386902 countsByYear W20043869022018 @default.
• W2004386902 countsByYear W20043869022019 @default.
• W2004386902 countsByYear W20043869022021 @default.
• W2004386902 countsByYear W20043869022022 @default.
• W2004386902 countsByYear W20043869022023 @default.
• W2004386902 crossrefType "journal-article" @default.
• W2004386902 hasAuthorship W2004386902A5007186830 @default.
• W2004386902 hasAuthorship W2004386902A5015440553 @default.
• W2004386902 hasAuthorship W2004386902A5018294657 @default.
• W2004386902 hasAuthorship W2004386902A5019401203 @default.
• W2004386902 hasAuthorship W2004386902A5032566816 @default.
• W2004386902 hasConcept C10146269 @default.
• W2004386902 hasConcept C126322002 @default.
• W2004386902 hasConcept C126894567 @default.
• W2004386902 hasConcept C134018914 @default.
• W2004386902 hasConcept C159641895 @default.
• W2004386902 hasConcept C2776125364 @default.
• W2004386902 hasConcept C2776174234 @default.
• W2004386902 hasConcept C2778596287 @default.
• W2004386902 hasConcept C2778653478 @default.
• W2004386902 hasConcept C2780026642 @default.
• W2004386902 hasConcept C2780306776 @default.
• W2004386902 hasConcept C2781203188 @default.
• W2004386902 hasConcept C71924100 @default.
• W2004386902 hasConceptScore W2004386902C10146269 @default.
• W2004386902 hasConceptScore W2004386902C126322002 @default.
• W2004386902 hasConceptScore W2004386902C126894567 @default.
• W2004386902 hasConceptScore W2004386902C134018914 @default.
• W2004386902 hasConceptScore W2004386902C159641895 @default.
• W2004386902 hasConceptScore W2004386902C2776125364 @default.
• W2004386902 hasConceptScore W2004386902C2776174234 @default.
• W2004386902 hasConceptScore W2004386902C2778596287 @default.
• W2004386902 hasConceptScore W2004386902C2778653478 @default.
• W2004386902 hasConceptScore W2004386902C2780026642 @default.
• W2004386902 hasConceptScore W2004386902C2780306776 @default.
• W2004386902 hasConceptScore W2004386902C2781203188 @default.
• W2004386902 hasConceptScore W2004386902C71924100 @default.
• W2004386902 hasIssue "3" @default.
• W2004386902 hasLocation W20043869021 @default.

• next