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- W2004389624 abstract "Guidelines on karyotyping infertile men before ICSI treatment are not consistent. Most guidelines recommend chromosomal screening in azoospermic and severe oligozoospermic men, because they are assumed to have the highest risk of abnormalities. We performed a retrospective cohort study in azoospermic men and men eligible for ICSI. We determined the prevalence of chromosomal abnormalities in relation to sperm concentration and compared our data to studies in the literature. A high prevalence of chromosomal abnormalities in azoospermic men was found, but no difference in the prevalence of abnormalities was seen between different sperm concentration categories in non-azoospermic men. This raises the question of who should be screened for chromosomal abnormalities before ICSI treatment. Considering the costs and benefits, we would propose limiting screening to infertile couples with non-obstructive azoospermia." @default.
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- W2004389624 date "2010-09-16" @default.
- W2004389624 modified "2023-09-27" @default.
- W2004389624 title "Who should be screened for chromosomal abnormalities before ICSI treatment?" @default.
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- W2004389624 doi "https://doi.org/10.1093/humrep/deq258" @default.
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