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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004390083> ?p ?o ?g. }

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• W2004390083 abstract "We report the synthesis and in vitro antimalarial activity of several new 4-amino- and 4-alkoxy-7-chloroquinolines carrying a linear dibasic side chain. Many of these chloroquine analogues have submicromolar antimalarial activity versus HB3 (chloroquine sensitive) and Dd2 (chloroquine resistant strain of Plasmodium falciparum) and low resistance indices were obtained in most cases. Importantly, compounds 11–15 and 24 proved to be more potent against Dd2 than chloroquine. Branching of the side chain structure proved detrimental to the activity against the CQR strain." @default.
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• W2004390083 date "2009-09-01" @default.
• W2004390083 modified "2023-10-18" @default.
• W2004390083 title "Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain" @default.
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• W2004390083 doi "https://doi.org/10.1016/j.bmc.2009.08.003" @default.
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