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- W2004396076 abstract "Endoscopic submucosal dissection (ESD) was initially developed for gastric cancer and is currently accepted as an established procedure for superficial cancer of the esophagus. The most important advantage of ESD compared with EMR is that it can provide a high en bloc resection rate and precise histologic assessment even for large lesions. 1 Ogura K. Okamoto M. Sugimoto T. et al. Efficacy and safety of endoscopic submucosal dissection for gastric cancer in patients with liver cirrhosis. Endoscopy. 2008; 40: 443-445 Crossref PubMed Scopus (33) Google Scholar On the other hand, the disadvantage of ESD is a higher risk of bleeding and perforation than for EMR. 2 Kakushima N. Fujishiro M. Endoscopic submucosal dissection for gastrointestinal neoplasms. World J Gastroenterol. 2008; 14: 2962-2967 Crossref PubMed Scopus (128) Google Scholar Previous reports described that esophageal ESD-related adverse events, such as postoperative bleeding and perforation, are considerably serious risks. 3 Fujishiro M. Yahagi N. Kakushima N. et al. Endoscopic submucosal dissection of esophageal squamous cell neoplasms. Clin Gastroenterol Hepatol. 2006; 4: 688-694 Abstract Full Text Full Text PDF PubMed Scopus (303) Google Scholar , 4 Kawahara Y, Hori K, Takenaka R, et al. Endoscopic submucosal dissection of esophageal cancer using the Mucosectom2 device: a feasibility study. Endoscopy. Epub 2013 Jul 24. Google Scholar , 5 Ishihara R. Iishi H. Uedo N. et al. Comparison of EMR and endoscopic submucosal dissection for en bloc resection of early esophageal cancers in Japan. Gastrointest Endosc. 2008; 68: 1066-1072 Abstract Full Text Full Text PDF PubMed Scopus (249) Google Scholar , 6 Repici A. Hassan C. Carlino A. et al. Endoscopic submucosal dissection in patients with early esophageal squamous cell carcinoma: results from a prospective Western series. Gastrointest Endosc. 2010; 71: 715-721 Abstract Full Text Full Text PDF PubMed Scopus (149) Google Scholar However, ESD for patients with cirrhosis may carry a higher risk of these adverse events because of the low platelet count, coagulopathy, and portal hypertensive gastroenteropathy, including esophageal varices, in these patients. As a result, endoscopists have been hesitant to apply ESD for the treatment of esophageal cancer in patients with cirrhosis." @default.
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- W2004396076 date "2014-04-01" @default.
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- W2004396076 title "The feasibility of endoscopic submucosal dissection for superficial esophageal cancer in patients with cirrhosis (with video)" @default.
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- W2004396076 doi "https://doi.org/10.1016/j.gie.2013.11.004" @default.
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