Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004397938> ?p ?o ?g. }
- W2004397938 endingPage "603" @default.
- W2004397938 startingPage "594" @default.
- W2004397938 abstract "Background: The most effective exercise dose has yet to be established for multiple sclerosis (MS). Objective: The aim of this study was to investigate the effect of different exercise intensities in people with MS. Methods: We completed a randomized comparator study of three cycling exercise intensities, with blinded assessment, was carried out in Oxford. Sixty-one adults with MS who fulfilled inclusion criteria were randomized at entry into the study, using a computer-generated list held by an exercise professional, into either: continuous (at 45% peak power, n = 20), intermittent (30 sec on, 30 sec off at 90% peak power, n = 21) or combined (10 min intermittent at 90% peak power then 10 min continuous at 45% peak power, n = 20) exercise for 20 min twice a week for 12 weeks in a leisure facility. Groups were assessed at: baseline, halfway (6 weeks), end intervention (12 weeks) and follow-up (24 weeks). Primary outcome measure was 2 min walk. Results: Fifty-five participants were included in the analysis ( n = continuous 20, intermittent 18, combined 17). No differences were found between groups. After 6 weeks, considering all participants, 2 min walk distance increased by 6.96 ± 2.56 m (95% CI: 1.81 to 12.10, effect size (es): 0.25, p < 0.01). The continuous group increased by 4.71 ± 4.24 m (95% CI: −3.80 to 13.22, es : 0.06), intermittent by 12.94 ± 4.71 m (95% CI: 3.97 to 21.92, es: 0.28) and combined by 3.22 ± 4.60 m (95% CI: −6.01 to 12.46, es: 0.04) . Two minute walk did not significantly change between further assessments. Between 6 and 12 weeks there was a drop in attendance that seemed to be associated with the intermittent and combined groups; these groups also had a greater number of adverse events (leg pain during cycling most common) and dropouts ( n = continuous 1, intermittent 5, combined 10). Considering all participants, 6 weeks of cycling exercise produced benefits in mobility that were maintained with further sessions. Conclusion: While no differences were found between groups, greater benefit may be associated with higher-intensity exercise, but this may be less well tolerated.CONSORT - trial registration number (ISRCTN89009719)" @default.
- W2004397938 created "2016-06-24" @default.
- W2004397938 creator A5019342019 @default.
- W2004397938 creator A5026584019 @default.
- W2004397938 creator A5029263137 @default.
- W2004397938 creator A5044028528 @default.
- W2004397938 creator A5063887990 @default.
- W2004397938 creator A5070482924 @default.
- W2004397938 creator A5070516661 @default.
- W2004397938 creator A5078627941 @default.
- W2004397938 creator A5087650984 @default.
- W2004397938 creator A5088241998 @default.
- W2004397938 date "2011-01-19" @default.
- W2004397938 modified "2023-10-01" @default.
- W2004397938 title "Exercise for multiple sclerosis: a single-blind randomized trial comparing three exercise intensities" @default.
- W2004397938 cites W1481903350 @default.
- W2004397938 cites W1556303558 @default.
- W2004397938 cites W1876524869 @default.
- W2004397938 cites W1974654819 @default.
- W2004397938 cites W1988746590 @default.
- W2004397938 cites W1994459030 @default.
- W2004397938 cites W2006331513 @default.
- W2004397938 cites W2031669983 @default.
- W2004397938 cites W2039043944 @default.
- W2004397938 cites W2053695178 @default.
- W2004397938 cites W2059164443 @default.
- W2004397938 cites W2065974896 @default.
- W2004397938 cites W2069614919 @default.
- W2004397938 cites W2080003981 @default.
- W2004397938 cites W2097735742 @default.
- W2004397938 cites W2100597227 @default.
- W2004397938 cites W2114242035 @default.
- W2004397938 cites W2128303179 @default.
- W2004397938 cites W2153406727 @default.
- W2004397938 cites W2165382255 @default.
- W2004397938 cites W2166354070 @default.
- W2004397938 cites W2168165963 @default.
- W2004397938 cites W4236805817 @default.
- W2004397938 doi "https://doi.org/10.1177/1352458510391836" @default.
- W2004397938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21247971" @default.
- W2004397938 hasPublicationYear "2011" @default.
- W2004397938 type Work @default.
- W2004397938 sameAs 2004397938 @default.
- W2004397938 citedByCount "88" @default.
- W2004397938 countsByYear W20043979382012 @default.
- W2004397938 countsByYear W20043979382013 @default.
- W2004397938 countsByYear W20043979382014 @default.
- W2004397938 countsByYear W20043979382015 @default.
- W2004397938 countsByYear W20043979382016 @default.
- W2004397938 countsByYear W20043979382017 @default.
- W2004397938 countsByYear W20043979382018 @default.
- W2004397938 countsByYear W20043979382019 @default.
- W2004397938 countsByYear W20043979382020 @default.
- W2004397938 countsByYear W20043979382021 @default.
- W2004397938 countsByYear W20043979382022 @default.
- W2004397938 countsByYear W20043979382023 @default.
- W2004397938 crossrefType "journal-article" @default.
- W2004397938 hasAuthorship W2004397938A5019342019 @default.
- W2004397938 hasAuthorship W2004397938A5026584019 @default.
- W2004397938 hasAuthorship W2004397938A5029263137 @default.
- W2004397938 hasAuthorship W2004397938A5044028528 @default.
- W2004397938 hasAuthorship W2004397938A5063887990 @default.
- W2004397938 hasAuthorship W2004397938A5070482924 @default.
- W2004397938 hasAuthorship W2004397938A5070516661 @default.
- W2004397938 hasAuthorship W2004397938A5078627941 @default.
- W2004397938 hasAuthorship W2004397938A5087650984 @default.
- W2004397938 hasAuthorship W2004397938A5088241998 @default.
- W2004397938 hasBestOaLocation W20043979382 @default.
- W2004397938 hasConcept C118552586 @default.
- W2004397938 hasConcept C126322002 @default.
- W2004397938 hasConcept C168563851 @default.
- W2004397938 hasConcept C1862650 @default.
- W2004397938 hasConcept C2780640218 @default.
- W2004397938 hasConcept C71924100 @default.
- W2004397938 hasConceptScore W2004397938C118552586 @default.
- W2004397938 hasConceptScore W2004397938C126322002 @default.
- W2004397938 hasConceptScore W2004397938C168563851 @default.
- W2004397938 hasConceptScore W2004397938C1862650 @default.
- W2004397938 hasConceptScore W2004397938C2780640218 @default.
- W2004397938 hasConceptScore W2004397938C71924100 @default.
- W2004397938 hasIssue "5" @default.
- W2004397938 hasLocation W20043979381 @default.
- W2004397938 hasLocation W20043979382 @default.
- W2004397938 hasLocation W20043979383 @default.
- W2004397938 hasOpenAccess W2004397938 @default.
- W2004397938 hasPrimaryLocation W20043979381 @default.
- W2004397938 hasRelatedWork W2089933404 @default.
- W2004397938 hasRelatedWork W2500513505 @default.
- W2004397938 hasRelatedWork W2530277175 @default.
- W2004397938 hasRelatedWork W2571673074 @default.
- W2004397938 hasRelatedWork W3125342416 @default.
- W2004397938 hasRelatedWork W3159250744 @default.
- W2004397938 hasRelatedWork W4206812446 @default.
- W2004397938 hasRelatedWork W4256514411 @default.
- W2004397938 hasRelatedWork W4292236216 @default.
- W2004397938 hasRelatedWork W2083697902 @default.
- W2004397938 hasVolume "17" @default.
- W2004397938 isParatext "false" @default.