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- W2004405144 abstract "In a bioassay guided phytochemical investigation of Toona ciliata (Fam. Meliaceae), a new hydroxy steroidal ketone, 12alpha-hydroxystigmast-4-en-3-one (1) was isolated from the petroleum ether extract of the plant together with two known steroids and three C-methyl coumarins. The structure of 1 was established by means of spectroscopic analyses. Compound 1 was found cytotoxic in a brine shrimp lethality bioassay with LC50 of 9.9 microg/ml and it also showed significant antitumor activity with Ti50 value of 14.1 microg/ml in a potato disc bioassay." @default.
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- W2004405144 date "2003-08-12" @default.
- W2004405144 modified "2023-09-30" @default.
- W2004405144 title "12α-Hydroxystigmast-4-en-3-one: A New Bioactive Steroid from Toona ciliata (Meliaceae)." @default.
- W2004405144 cites W3199652382 @default.
- W2004405144 doi "https://doi.org/10.1002/chin.200332126" @default.
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