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- W2004409595 abstract "A spontaneous dynamic kinetic resolution of 8-amino-5,6,7,8-tetrahydroquinoline 1 was observed in the presence of Candida antarctica Lipase B, in which a >60% yield of (R)-acetamide [(R)-2] was isolated from the racemic amine. The spontaneous formation of ketone 3, followed by a condensation/hydrolysis sequence with the remaining (S)-amine 1, via enamine 4, provides the necessary racemization pathway." @default.
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- W2004409595 date "2006-12-07" @default.
- W2004409595 modified "2023-10-18" @default.
- W2004409595 title "Spontaneous Enzymatically Mediated Dynamic Kinetic Resolution of 8-Amino-5,6,7,8-tetrahydroquinoline" @default.
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- W2004409595 doi "https://doi.org/10.1021/jo062037t" @default.
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