Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004412029> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2004412029 endingPage "262" @default.
- W2004412029 startingPage "257" @default.
- W2004412029 abstract "Published evidence suggests that botulinum toxin type A (BTX-A) is an effective treatment for crow's feet. However, few dose-ranging studies have been performed.To assess the safety and efficacy of a single treatment with one of four doses of BTX-A (Botox/Vistabel, Allergan Inc) compared with placebo for the improvement of crow's feet.Subjects received a single bilateral treatment of 18, 12, 6, or 3 U of BTX-A or placebo injected into the lateral aspect of the orbicularis oculi muscle (parallel-group, double-blind design). Investigators and subjects rated crow's feet severity at maximum smile on day 7 and at 30-day intervals from days 30 to 180.As observed by both investigators and subjects, all doses of BTX-A resulted in improvements in crow's feet severity when compared with placebo. A dose-dependent treatment effect for efficacy was observed, with higher doses having an increased magnitude and duration of effect. However, a clear differentiation between the 18 U and 12 U doses was not apparent. Few adverse events were reported, with no statistically significant differences between BTX-A and placebo in the incidence of subjects experiencing adverse events.BTX-A is safe and effective in decreasing the severity of crow's feet, with 12 U per side suggested as the most appropriate dose." @default.
- W2004412029 created "2016-06-24" @default.
- W2004412029 creator A5000630505 @default.
- W2004412029 creator A5030356739 @default.
- W2004412029 creator A5056248257 @default.
- W2004412029 creator A5072890715 @default.
- W2004412029 creator A5076323245 @default.
- W2004412029 creator A5079870669 @default.
- W2004412029 date "2006-03-21" @default.
- W2004412029 modified "2023-10-10" @default.
- W2004412029 title "Double-Blind, Randomized, Placebo-Controlled, Dose-Response Study of the Safety and Efficacy of Botulinum Toxin Type A in Subjects with Crow's Feet" @default.
- W2004412029 cites W1965278980 @default.
- W2004412029 cites W1978910356 @default.
- W2004412029 cites W2053818000 @default.
- W2004412029 cites W2060774155 @default.
- W2004412029 cites W2063723638 @default.
- W2004412029 cites W2070832629 @default.
- W2004412029 cites W2135855878 @default.
- W2004412029 cites W4226153170 @default.
- W2004412029 cites W4363610867 @default.
- W2004412029 doi "https://doi.org/10.1111/j.1524-4725.2005.31070" @default.
- W2004412029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15841623" @default.
- W2004412029 hasPublicationYear "2006" @default.
- W2004412029 type Work @default.
- W2004412029 sameAs 2004412029 @default.
- W2004412029 citedByCount "47" @default.
- W2004412029 countsByYear W20044120292012 @default.
- W2004412029 countsByYear W20044120292013 @default.
- W2004412029 countsByYear W20044120292014 @default.
- W2004412029 countsByYear W20044120292015 @default.
- W2004412029 countsByYear W20044120292016 @default.
- W2004412029 countsByYear W20044120292017 @default.
- W2004412029 countsByYear W20044120292018 @default.
- W2004412029 countsByYear W20044120292019 @default.
- W2004412029 countsByYear W20044120292020 @default.
- W2004412029 countsByYear W20044120292021 @default.
- W2004412029 countsByYear W20044120292022 @default.
- W2004412029 countsByYear W20044120292023 @default.
- W2004412029 crossrefType "journal-article" @default.
- W2004412029 hasAuthorship W2004412029A5000630505 @default.
- W2004412029 hasAuthorship W2004412029A5030356739 @default.
- W2004412029 hasAuthorship W2004412029A5056248257 @default.
- W2004412029 hasAuthorship W2004412029A5072890715 @default.
- W2004412029 hasAuthorship W2004412029A5076323245 @default.
- W2004412029 hasAuthorship W2004412029A5079870669 @default.
- W2004412029 hasConcept C120665830 @default.
- W2004412029 hasConcept C121332964 @default.
- W2004412029 hasConcept C126322002 @default.
- W2004412029 hasConcept C141071460 @default.
- W2004412029 hasConcept C142724271 @default.
- W2004412029 hasConcept C168563851 @default.
- W2004412029 hasConcept C197934379 @default.
- W2004412029 hasConcept C204787440 @default.
- W2004412029 hasConcept C27081682 @default.
- W2004412029 hasConcept C2777478456 @default.
- W2004412029 hasConcept C2991744798 @default.
- W2004412029 hasConcept C42219234 @default.
- W2004412029 hasConcept C61511704 @default.
- W2004412029 hasConcept C71924100 @default.
- W2004412029 hasConceptScore W2004412029C120665830 @default.
- W2004412029 hasConceptScore W2004412029C121332964 @default.
- W2004412029 hasConceptScore W2004412029C126322002 @default.
- W2004412029 hasConceptScore W2004412029C141071460 @default.
- W2004412029 hasConceptScore W2004412029C142724271 @default.
- W2004412029 hasConceptScore W2004412029C168563851 @default.
- W2004412029 hasConceptScore W2004412029C197934379 @default.
- W2004412029 hasConceptScore W2004412029C204787440 @default.
- W2004412029 hasConceptScore W2004412029C27081682 @default.
- W2004412029 hasConceptScore W2004412029C2777478456 @default.
- W2004412029 hasConceptScore W2004412029C2991744798 @default.
- W2004412029 hasConceptScore W2004412029C42219234 @default.
- W2004412029 hasConceptScore W2004412029C61511704 @default.
- W2004412029 hasConceptScore W2004412029C71924100 @default.
- W2004412029 hasIssue "3" @default.
- W2004412029 hasLocation W20044120291 @default.
- W2004412029 hasLocation W20044120292 @default.
- W2004412029 hasOpenAccess W2004412029 @default.
- W2004412029 hasPrimaryLocation W20044120291 @default.
- W2004412029 hasRelatedWork W2003938723 @default.
- W2004412029 hasRelatedWork W2006175019 @default.
- W2004412029 hasRelatedWork W2029595472 @default.
- W2004412029 hasRelatedWork W2047967234 @default.
- W2004412029 hasRelatedWork W2066861358 @default.
- W2004412029 hasRelatedWork W2118496982 @default.
- W2004412029 hasRelatedWork W2275480158 @default.
- W2004412029 hasRelatedWork W2439875401 @default.
- W2004412029 hasRelatedWork W4238867864 @default.
- W2004412029 hasRelatedWork W2525756941 @default.
- W2004412029 hasVolume "31" @default.
- W2004412029 isParatext "false" @default.
- W2004412029 isRetracted "false" @default.
- W2004412029 magId "2004412029" @default.
- W2004412029 workType "article" @default.