FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004413378> ?p ?o ?g. }

• W2004413378 endingPage "24" @default.
• W2004413378 startingPage "13" @default.
• W2004413378 abstract "Conformational flexibility of molecules in solution implies that different conformers contribute to the NMR signal. This may lead to internal inconsistencies in the 2D NOE-derived interproton distance restraints and to conflict with scalar coupling-based torsion angle restraints. Such inconsistencies have been revealed and analyzed for the DNA octamer GTATAATG.CATATTAC, containing the Pribnow box consensus sequence. A number of subsets of distance restraints were constructed and used in the restrained Monte Carlo refinement of different double-helical conformers. The probabilities of conformers were then calculated by a quadratic programming algorithm, minimizing a relaxation rate-base residual index. The calculated distribution of conformers agrees with the experimental NOE data as an ensemble better than any single structure. A comparison with the results of this procedure, which we term PARSE (Probability Assessment via Relaxation rates of a Structural Ensemble), to an alternative method to generate solution ensembles showed, however, that the detailed multi-conformational description of solution DNA structure remains ambiguous at this stage. Nevertheless, some ensemble properties can be deduced with confidence, the most prominent being a distribution of sugar puckers with minor populations in the N-region and major populations in the S-region. Importantly, such a distribution is in accord with the analysis of independent experimental data--deoxyribose proton-proton scalar coupling constants." @default.
• W2004413378 created "2016-06-24" @default.
• W2004413378 creator A5010476812 @default.
• W2004413378 creator A5012251433 @default.
• W2004413378 creator A5063451200 @default.
• W2004413378 creator A5071117313 @default.
• W2004413378 date "1995-01-01" @default.
• W2004413378 modified "2023-09-29" @default.
• W2004413378 title "Probability assessment of conformational ensembles: sugar repuckering in a DNA duplex in solution" @default.
• W2004413378 cites W1508962890 @default.
• W2004413378 cites W1565638922 @default.
• W2004413378 cites W1969061680 @default.
• W2004413378 cites W1975851628 @default.
• W2004413378 cites W1979936737 @default.
• W2004413378 cites W1980195457 @default.
• W2004413378 cites W1987121428 @default.
• W2004413378 cites W1987352448 @default.
• W2004413378 cites W1988993336 @default.
• W2004413378 cites W1990227667 @default.
• W2004413378 cites W1992109326 @default.
• W2004413378 cites W1994514296 @default.
• W2004413378 cites W2001699079 @default.
• W2004413378 cites W2011002705 @default.
• W2004413378 cites W2011917559 @default.
• W2004413378 cites W2019523676 @default.
• W2004413378 cites W2024300887 @default.
• W2004413378 cites W2044999527 @default.
• W2004413378 cites W2049172861 @default.
• W2004413378 cites W2062410769 @default.
• W2004413378 cites W2067006059 @default.
• W2004413378 cites W2068217205 @default.
• W2004413378 cites W2069908548 @default.
• W2004413378 cites W2077379869 @default.
• W2004413378 cites W2079961585 @default.
• W2004413378 cites W2082724643 @default.
• W2004413378 cites W2091940579 @default.
• W2004413378 cites W2092712910 @default.
• W2004413378 cites W2123242549 @default.
• W2004413378 cites W2174021414 @default.
• W2004413378 cites W3021884971 @default.
• W2004413378 cites W4249593510 @default.
• W2004413378 cites W967123368 @default.
• W2004413378 doi "https://doi.org/10.1016/s0006-3495(95)80181-5" @default.
• W2004413378 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1281656" @default.
• W2004413378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7711233" @default.
• W2004413378 hasPublicationYear "1995" @default.
• W2004413378 type Work @default.
• W2004413378 sameAs 2004413378 @default.
• W2004413378 citedByCount "71" @default.
• W2004413378 countsByYear W20044133782016 @default.
• W2004413378 countsByYear W20044133782018 @default.
• W2004413378 crossrefType "journal-article" @default.
• W2004413378 hasAuthorship W2004413378A5010476812 @default.
• W2004413378 hasAuthorship W2004413378A5012251433 @default.
• W2004413378 hasAuthorship W2004413378A5063451200 @default.
• W2004413378 hasAuthorship W2004413378A5071117313 @default.
• W2004413378 hasBestOaLocation W20044133781 @default.
• W2004413378 hasConcept C105795698 @default.
• W2004413378 hasConcept C112887158 @default.
• W2004413378 hasConcept C121332964 @default.
• W2004413378 hasConcept C121864883 @default.
• W2004413378 hasConcept C147597530 @default.
• W2004413378 hasConcept C15744967 @default.
• W2004413378 hasConcept C178790620 @default.
• W2004413378 hasConcept C185592680 @default.
• W2004413378 hasConcept C18705241 @default.
• W2004413378 hasConcept C19499675 @default.
• W2004413378 hasConcept C2776029896 @default.
• W2004413378 hasConcept C32909587 @default.
• W2004413378 hasConcept C33923547 @default.
• W2004413378 hasConcept C77805123 @default.
• W2004413378 hasConcept C89025888 @default.
• W2004413378 hasConceptScore W2004413378C105795698 @default.
• W2004413378 hasConceptScore W2004413378C112887158 @default.
• W2004413378 hasConceptScore W2004413378C121332964 @default.
• W2004413378 hasConceptScore W2004413378C121864883 @default.
• W2004413378 hasConceptScore W2004413378C147597530 @default.
• W2004413378 hasConceptScore W2004413378C15744967 @default.
• W2004413378 hasConceptScore W2004413378C178790620 @default.
• W2004413378 hasConceptScore W2004413378C185592680 @default.
• W2004413378 hasConceptScore W2004413378C18705241 @default.
• W2004413378 hasConceptScore W2004413378C19499675 @default.
• W2004413378 hasConceptScore W2004413378C2776029896 @default.
• W2004413378 hasConceptScore W2004413378C32909587 @default.
• W2004413378 hasConceptScore W2004413378C33923547 @default.
• W2004413378 hasConceptScore W2004413378C77805123 @default.
• W2004413378 hasConceptScore W2004413378C89025888 @default.
• W2004413378 hasIssue "1" @default.
• W2004413378 hasLocation W20044133781 @default.
• W2004413378 hasLocation W20044133782 @default.
• W2004413378 hasLocation W20044133783 @default.
• W2004413378 hasLocation W20044133784 @default.
• W2004413378 hasOpenAccess W2004413378 @default.
• W2004413378 hasPrimaryLocation W20044133781 @default.
• W2004413378 hasRelatedWork W1992619981 @default.
• W2004413378 hasRelatedWork W1992705843 @default.
• W2004413378 hasRelatedWork W2002988671 @default.
• W2004413378 hasRelatedWork W2049189568 @default.

• next