Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004451755> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2004451755 abstract "Interferons exert antiviral, antiproliferative, and immunomodulatory effects on target cells. The effectiveness of interferon treatment can be followed by measuring parameters involved in interferon action. The clinical effectiveness of interferons has been proved in the human papillomavirus (HPV)-associated disease condyloma acuminatum. Because one of the most important goals in the treatment of this condition is the elimination of recurrences, it was asked whether clinically effective interferon therapy was associated with elimination of HPV DNA. The authors used a polymerase chain reaction-based method to detect the HPV from minute amounts of clinical biopsies. Human papillomavirus-transformed cell lines or cloned HPV genomes served as different copy number controls. The intensity ratio of L1 HPV and the human beta-globin (which served as an internal control) fragments was determined and used for estimation of HPV copy number in different biopsies. A direct effect of interferon treatment on HPV viral genome copies was observed in a group of responder patients, but not in the clinically resistant group. With these data, a correlation was found between virologic data and clinical findings. This method also can be used in other lesions to determine the HPV copy number and HPV type and may have value in determining the antiviral activities of other agents used in the treatment of HPV-related lesions." @default.
- W2004451755 created "2016-06-24" @default.
- W2004451755 creator A5024767194 @default.
- W2004451755 creator A5040509939 @default.
- W2004451755 creator A5082988463 @default.
- W2004451755 date "1995-07-01" @default.
- W2004451755 modified "2023-09-24" @default.
- W2004451755 title "Effect of Interferon Therapy on Human Papillomavirus Copy Number in Patients With Condyloma Acuminatum" @default.
- W2004451755 cites W1572076229 @default.
- W2004451755 cites W1657284351 @default.
- W2004451755 cites W1928958735 @default.
- W2004451755 cites W1972778690 @default.
- W2004451755 cites W1981066689 @default.
- W2004451755 cites W1981440527 @default.
- W2004451755 cites W1986121641 @default.
- W2004451755 cites W2004204418 @default.
- W2004451755 cites W2062896803 @default.
- W2004451755 cites W2087998229 @default.
- W2004451755 cites W2094498153 @default.
- W2004451755 cites W2105904300 @default.
- W2004451755 cites W2130094418 @default.
- W2004451755 cites W2140100637 @default.
- W2004451755 cites W2314781696 @default.
- W2004451755 cites W2340232093 @default.
- W2004451755 cites W2409754427 @default.
- W2004451755 cites W2411137245 @default.
- W2004451755 cites W2419310763 @default.
- W2004451755 cites W2969431143 @default.
- W2004451755 doi "https://doi.org/10.1097/00000441-199507000-00006" @default.
- W2004451755 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7541607" @default.
- W2004451755 hasPublicationYear "1995" @default.
- W2004451755 type Work @default.
- W2004451755 sameAs 2004451755 @default.
- W2004451755 citedByCount "13" @default.
- W2004451755 countsByYear W20044517552019 @default.
- W2004451755 crossrefType "journal-article" @default.
- W2004451755 hasAuthorship W2004451755A5024767194 @default.
- W2004451755 hasAuthorship W2004451755A5040509939 @default.
- W2004451755 hasAuthorship W2004451755A5082988463 @default.
- W2004451755 hasConcept C104317684 @default.
- W2004451755 hasConcept C121608353 @default.
- W2004451755 hasConcept C126322002 @default.
- W2004451755 hasConcept C159047783 @default.
- W2004451755 hasConcept C203014093 @default.
- W2004451755 hasConcept C2522874641 @default.
- W2004451755 hasConcept C2776178377 @default.
- W2004451755 hasConcept C2776270601 @default.
- W2004451755 hasConcept C2778220009 @default.
- W2004451755 hasConcept C2778580637 @default.
- W2004451755 hasConcept C2781228144 @default.
- W2004451755 hasConcept C2909179924 @default.
- W2004451755 hasConcept C2909217500 @default.
- W2004451755 hasConcept C2994532551 @default.
- W2004451755 hasConcept C49105822 @default.
- W2004451755 hasConcept C54355233 @default.
- W2004451755 hasConcept C71924100 @default.
- W2004451755 hasConcept C86803240 @default.
- W2004451755 hasConceptScore W2004451755C104317684 @default.
- W2004451755 hasConceptScore W2004451755C121608353 @default.
- W2004451755 hasConceptScore W2004451755C126322002 @default.
- W2004451755 hasConceptScore W2004451755C159047783 @default.
- W2004451755 hasConceptScore W2004451755C203014093 @default.
- W2004451755 hasConceptScore W2004451755C2522874641 @default.
- W2004451755 hasConceptScore W2004451755C2776178377 @default.
- W2004451755 hasConceptScore W2004451755C2776270601 @default.
- W2004451755 hasConceptScore W2004451755C2778220009 @default.
- W2004451755 hasConceptScore W2004451755C2778580637 @default.
- W2004451755 hasConceptScore W2004451755C2781228144 @default.
- W2004451755 hasConceptScore W2004451755C2909179924 @default.
- W2004451755 hasConceptScore W2004451755C2909217500 @default.
- W2004451755 hasConceptScore W2004451755C2994532551 @default.
- W2004451755 hasConceptScore W2004451755C49105822 @default.
- W2004451755 hasConceptScore W2004451755C54355233 @default.
- W2004451755 hasConceptScore W2004451755C71924100 @default.
- W2004451755 hasConceptScore W2004451755C86803240 @default.
- W2004451755 hasLocation W20044517551 @default.
- W2004451755 hasLocation W20044517552 @default.
- W2004451755 hasOpenAccess W2004451755 @default.
- W2004451755 hasPrimaryLocation W20044517551 @default.
- W2004451755 hasRelatedWork W1965068912 @default.
- W2004451755 hasRelatedWork W1991190921 @default.
- W2004451755 hasRelatedWork W2004451755 @default.
- W2004451755 hasRelatedWork W2028844518 @default.
- W2004451755 hasRelatedWork W2032373093 @default.
- W2004451755 hasRelatedWork W2058201205 @default.
- W2004451755 hasRelatedWork W2118937887 @default.
- W2004451755 hasRelatedWork W2127791233 @default.
- W2004451755 hasRelatedWork W2379701289 @default.
- W2004451755 hasRelatedWork W2740454410 @default.
- W2004451755 isParatext "false" @default.
- W2004451755 isRetracted "false" @default.
- W2004451755 magId "2004451755" @default.
- W2004451755 workType "article" @default.