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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004457415> ?p ?o ?g. }

• W2004457415 abstract "Gi alpha proteins, members of the G protein signal transduction family, include a small number of polypeptides: Gi alpha 1 (GNAI1), Gi alpha 2 (GNAI2), and Gi alpha 3 (GNAI3). A cDNA for the human GNAI2 gene has been isolated from a human T-cell library and is mapped by chromosomal in situ hybridization to the short arm of chromosome 3 at 3p21. A related sequence, GNAI2L, is mapped by in situ hybridization to the short arm of chromosome 12 at p12-p13. These mapping results are further supported by amplification of GNAI2-specific sequences in a monochromosomal human/rodent somatic cell hybrid containing only human chromosome 3. Of note, these assignments are to chromosome regions in which other G proteins reside. Localization of GNAI2 to 3p21 is of great interest as this region of the short arm of chromosome 3 is frequently involved in rearrangements in various human tumors." @default.
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• W2004457415 date "1992-01-01" @default.
• W2004457415 modified "2023-09-23" @default.
• W2004457415 title "Regional localization of the human G protein αi2 (GNAI2) gene: Assignment to 3p21 and a related sequence (GNAI2L) to 12p12–p13" @default.
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• W2004457415 doi "https://doi.org/10.1016/0888-7543(92)90414-n" @default.
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