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- W2004496952 abstract "Abstract A new gene vector, cationized Lycium barbarum polysaccharides (cLBP) nanoparticles, prepared with different amine compounds for non-viral delivery of plasmid DNA encoding for transforming growth factor beta 1 (TGFβ-1) was developed and the efficiency of these nanoparticles to transfect rat mesenchymal stem cells in vitro was determined. The spherical cLBP-plasmid TGFβ-1 nanoparticles were 160–330 nm in diameter and can retard the migration of plasmid TGFβ-1 in electrophoresis. Ethylenediamine-LBP nanoparticles manifested better transfection efficiency compared with spermine-LBP and polyethylenimine-LBP nanostructures. At M cLBP /M pTGFβ-1 ratio 80, maximum TGFβ-1 expression mediated by Ethylenediamine-LBP was much higher than both PEI ( p p" @default.
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- W2004496952 date "2011-10-01" @default.
- W2004496952 modified "2023-10-16" @default.
- W2004496952 title "Efficient gene transfer into rat mesenchymal stem cells with cationized Lycium barbarum polysaccharides nanoparticles" @default.
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- W2004496952 doi "https://doi.org/10.1016/j.carbpol.2011.06.073" @default.
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