FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004525530> ?p ?o ?g. }

• W2004525530 endingPage "350" @default.
• W2004525530 startingPage "339" @default.
• W2004525530 abstract "1. ATP-mediated Ca2+ signalling was studied in freshly isolated rat portal vein myocytes by means of a laser confocal microscope and the patch-clamp technique. 2. In vascular myocytes held at -60 mV, ATP induced a large inward current that was supported mainly by activation of P2X1 receptors, although other P2X receptor subtypes (P2X3, P2X4 and P2X5) were revealed by reverse transcription-polymerase chain reaction. 3. Confocal Ca2+ measurements revealed that ATP-mediated Ca2+ responses started at initiation sites where spontaneous or triggered Ca2+ sparks were not detected, whereas membrane depolarizations triggered Ca2+ waves by repetitive activation of Ca2+ sparks from a single initiation site. 4. ATP-mediated Ca2+ responses depended on Ca2+ influx through non-selective cation channels that activated, in turn, Ca2+ release from the intracellular store via ryanodine receptors (RYRs). Using specific antibodies directed against the RYR subtypes, we show that ATP-mediated Ca2+ release requires, at least, RYR2, but not RYR3. 5. Our results suggest that, in vascular myocytes, Ca2+ influx through P2X1 receptors may trigger Ca2+-induced Ca2+ release at intracellular sites where RYRs are not clustered." @default.
• W2004525530 created "2016-06-24" @default.
• W2004525530 creator A5006688316 @default.
• W2004525530 creator A5016750178 @default.
• W2004525530 creator A5017864907 @default.
• W2004525530 creator A5038108527 @default.
• W2004525530 creator A5041735947 @default.
• W2004525530 creator A5058673488 @default.
• W2004525530 creator A5065712165 @default.
• W2004525530 date "2001-10-01" @default.
• W2004525530 modified "2023-10-18" @default.
• W2004525530 title "Calcium signalling through nucleotide receptor P2X1 in rat portal vein myocytes" @default.
• W2004525530 cites W128062084 @default.
• W2004525530 cites W1608870321 @default.
• W2004525530 cites W1857532475 @default.
• W2004525530 cites W1861890207 @default.
• W2004525530 cites W1944559560 @default.
• W2004525530 cites W1946415498 @default.
• W2004525530 cites W1970488832 @default.
• W2004525530 cites W1974249330 @default.
• W2004525530 cites W1984290551 @default.
• W2004525530 cites W1984841286 @default.
• W2004525530 cites W1985127217 @default.
• W2004525530 cites W1988692082 @default.
• W2004525530 cites W1990140279 @default.
• W2004525530 cites W1993569708 @default.
• W2004525530 cites W2000551229 @default.
• W2004525530 cites W2006478734 @default.
• W2004525530 cites W2009935511 @default.
• W2004525530 cites W2015001023 @default.
• W2004525530 cites W2016811193 @default.
• W2004525530 cites W2028684902 @default.
• W2004525530 cites W2028986208 @default.
• W2004525530 cites W2057947793 @default.
• W2004525530 cites W2065659859 @default.
• W2004525530 cites W2071613709 @default.
• W2004525530 cites W2077635738 @default.
• W2004525530 cites W2078854095 @default.
• W2004525530 cites W2087231244 @default.
• W2004525530 cites W2091148180 @default.
• W2004525530 cites W2092296126 @default.
• W2004525530 cites W2092437783 @default.
• W2004525530 cites W2099757747 @default.
• W2004525530 cites W2109311512 @default.
• W2004525530 cites W2140313595 @default.
• W2004525530 cites W2140327830 @default.
• W2004525530 cites W2150062642 @default.
• W2004525530 cites W2160753550 @default.
• W2004525530 cites W2292001455 @default.
• W2004525530 cites W2332159849 @default.
• W2004525530 cites W2335571152 @default.
• W2004525530 cites W2404609735 @default.
• W2004525530 doi "https://doi.org/10.1111/j.1469-7793.2001.0339c.xd" @default.
• W2004525530 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2278886" @default.
• W2004525530 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11600670" @default.
• W2004525530 hasPublicationYear "2001" @default.
• W2004525530 type Work @default.
• W2004525530 sameAs 2004525530 @default.
• W2004525530 citedByCount "23" @default.
• W2004525530 countsByYear W20045255302012 @default.
• W2004525530 countsByYear W20045255302013 @default.
• W2004525530 countsByYear W20045255302014 @default.
• W2004525530 countsByYear W20045255302015 @default.
• W2004525530 countsByYear W20045255302016 @default.
• W2004525530 crossrefType "journal-article" @default.
• W2004525530 hasAuthorship W2004525530A5006688316 @default.
• W2004525530 hasAuthorship W2004525530A5016750178 @default.
• W2004525530 hasAuthorship W2004525530A5017864907 @default.
• W2004525530 hasAuthorship W2004525530A5038108527 @default.
• W2004525530 hasAuthorship W2004525530A5041735947 @default.
• W2004525530 hasAuthorship W2004525530A5058673488 @default.
• W2004525530 hasAuthorship W2004525530A5065712165 @default.
• W2004525530 hasBestOaLocation W20045255302 @default.
• W2004525530 hasConcept C113217602 @default.
• W2004525530 hasConcept C12554922 @default.
• W2004525530 hasConcept C134018914 @default.
• W2004525530 hasConcept C170493617 @default.
• W2004525530 hasConcept C178790620 @default.
• W2004525530 hasConcept C185592680 @default.
• W2004525530 hasConcept C190712762 @default.
• W2004525530 hasConcept C207200792 @default.
• W2004525530 hasConcept C2779395532 @default.
• W2004525530 hasConcept C2992686903 @default.
• W2004525530 hasConcept C519063684 @default.
• W2004525530 hasConcept C55493867 @default.
• W2004525530 hasConcept C79879829 @default.
• W2004525530 hasConcept C86803240 @default.
• W2004525530 hasConcept C95444343 @default.
• W2004525530 hasConceptScore W2004525530C113217602 @default.
• W2004525530 hasConceptScore W2004525530C12554922 @default.
• W2004525530 hasConceptScore W2004525530C134018914 @default.
• W2004525530 hasConceptScore W2004525530C170493617 @default.
• W2004525530 hasConceptScore W2004525530C178790620 @default.
• W2004525530 hasConceptScore W2004525530C185592680 @default.
• W2004525530 hasConceptScore W2004525530C190712762 @default.
• W2004525530 hasConceptScore W2004525530C207200792 @default.
• W2004525530 hasConceptScore W2004525530C2779395532 @default.
• W2004525530 hasConceptScore W2004525530C2992686903 @default.

• next