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• W2004532068 abstract "A hypothesis implicating dopamine in depression was proposed over 15 years ago (Randrup et al 1975). The identification of multiple new subtypes of dopamine receptors and evolving views regarding the function of the dopamine systems in the brain require a reexamination of this hypothesis. Results from studies in depression, Parkinson's disease, and animal models of depression suggest a deficiency of dopamine in depression. Dopamine precursors, dopamine agonists, and dopamine reuptake inhibitors show therapeutic efficacy in depression. Electroconvulsive therapy (ECT) and standard pharmacological antidepressants enhance dopamine function. Studies using receptor-specific drugs in clinical trials and neuroimaging studies are needed to further clarify the role of dopamine in depression." @default.
• W2004532068 created "2016-06-24" @default.
• W2004532068 creator A5037602769 @default.
• W2004532068 creator A5042260113 @default.
• W2004532068 date "1992-07-01" @default.
• W2004532068 modified "2023-09-30" @default.
• W2004532068 title "Role of the dopaminergic system in depression" @default.
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