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- W2004536758 abstract "Biliary atresia is a rare disease of unclear etiology, in which obstruction of the biliary tree causes severe cholestasis leading to cirrhosis and ultimately death if left untreated. Biliary atresia is the leading cause of neonatal cholestasis and the most frequent indication for pediatric liver transplantation. Any infant with persistent jaundice beyond 2 weeks of life needs to be evaluated for biliary atresia with fractionation of the bilirubin into conjugated and unconjugated portions. Early performance of a hepatoportoenterostomy in the first 45 days of life to restore bile flow and lessen further damage to the liver is thought to optimize outcome. Despite surgery, progressive liver scarring occurs, and 80% of patients with biliary atresia will require liver transplantation during childhood." @default.
- W2004536758 created "2016-06-24" @default.
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- W2004536758 date "2015-08-01" @default.
- W2004536758 modified "2023-10-15" @default.
- W2004536758 title "Biliary Atresia" @default.
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- W2004536758 doi "https://doi.org/10.1097/mpg.0000000000000755" @default.
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