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- W2004548853 abstract "Thirty-two fully formed vital teeth of four adult cynolmolgus monkeys were endodontically prepared to simulate conditions of an open apex. The apical 2 to 5 mm of 24 teeth were filled with freeze-dried cortical bone. The eight remaining teeth received no implant material and served as controls. All the teeth were obturated with gutta-percha. The monkeys were killed at 5, 14, 24, and 28 weeks, and specimens were prepared for histologic examination. The early specimens showed localized acute inflammation with general organizational healing apically, whereas later specimens showed osseous healing. Some experimental teeth had mineralized tissue resembling osteocementum occupying the canal. Freeze-dried cortical bone was found to be a biocompatible material that can be used effectively as a substitute barrier against which gutta-percha can be condensed in mechanically prepared open-apexed monkeys' teeth." @default.
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- W2004548853 date "1982-05-01" @default.
- W2004548853 modified "2023-09-27" @default.
- W2004548853 title "A study of freeze-dried (lyophilized) cortical bone used as an apical barrier in adult monkey teeth" @default.
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- W2004548853 doi "https://doi.org/10.1016/s0099-2399(82)80358-0" @default.
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