FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004564116> ?p ?o ?g. }

• W2004564116 endingPage "522" @default.
• W2004564116 startingPage "514" @default.
• W2004564116 abstract "We report an unusual phenotype of B cells in a patient with X-linked agammaglobulinemia (XLA), and cellular evidence for Lyonization of B cells from his mother and sister. The patient has a failure of B cell maturation at the stage of early B lymphocytes, associated with production of D(mu delta) H chain. The phenotype of his B cells includes: (a) limitation to expression of the mu and delta H chain isotypes, (b) production of mu and delta H chains of reduced size and (c) delayed expression of L chain. Peripheral blood and B cell lines from the patient's mother and sister include 50% cells that express H chain without L chain. B cell lines from the mother and sister produce full-length mu and gamma H chains and truncated mu and delta chains corresponding to the H chains produced by the patient's B cells. Clones with normal and XLA phenotype have been isolated from B cell lines derived from the patient's mother. We conclude that the dimorphism of mother's and sister's B cells results from Lyonization, implying that the gene defect in XLA is intrinsic to B lymphocytes." @default.
• W2004564116 created "2016-06-24" @default.
• W2004564116 creator A5021242676 @default.
• W2004564116 creator A5026268117 @default.
• W2004564116 creator A5077155945 @default.
• W2004564116 date "1988-02-01" @default.
• W2004564116 modified "2023-10-12" @default.
• W2004564116 title "B lymphocytes from X-linked agammaglobulinemia. Delayed expression of light chain and demonstration of Lyonization in carriers." @default.
• W2004564116 cites W1518814649 @default.
• W2004564116 cites W1544157772 @default.
• W2004564116 cites W1586623480 @default.
• W2004564116 cites W1593139252 @default.
• W2004564116 cites W1962439838 @default.
• W2004564116 cites W1963984598 @default.
• W2004564116 cites W1968440687 @default.
• W2004564116 cites W1986477747 @default.
• W2004564116 cites W1988671772 @default.
• W2004564116 cites W1989170042 @default.
• W2004564116 cites W1996544873 @default.
• W2004564116 cites W2005554448 @default.
• W2004564116 cites W2007618593 @default.
• W2004564116 cites W2014669590 @default.
• W2004564116 cites W2021923341 @default.
• W2004564116 cites W2025387497 @default.
• W2004564116 cites W2029146706 @default.
• W2004564116 cites W2029844299 @default.
• W2004564116 cites W2035800046 @default.
• W2004564116 cites W2041473255 @default.
• W2004564116 cites W2046902532 @default.
• W2004564116 cites W2056935274 @default.
• W2004564116 cites W2061488856 @default.
• W2004564116 cites W2064208630 @default.
• W2004564116 cites W2073905298 @default.
• W2004564116 cites W2075964214 @default.
• W2004564116 cites W2085514731 @default.
• W2004564116 cites W2092900444 @default.
• W2004564116 cites W2140236115 @default.
• W2004564116 cites W2166775746 @default.
• W2004564116 cites W2170677264 @default.
• W2004564116 cites W2324316160 @default.
• W2004564116 cites W2409437370 @default.
• W2004564116 cites W4237874187 @default.
• W2004564116 doi "https://doi.org/10.1172/jci113349" @default.
• W2004564116 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/329599" @default.
• W2004564116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3123521" @default.
• W2004564116 hasPublicationYear "1988" @default.
• W2004564116 type Work @default.
• W2004564116 sameAs 2004564116 @default.
• W2004564116 citedByCount "11" @default.
• W2004564116 countsByYear W20045641162017 @default.
• W2004564116 crossrefType "journal-article" @default.
• W2004564116 hasAuthorship W2004564116A5021242676 @default.
• W2004564116 hasAuthorship W2004564116A5026268117 @default.
• W2004564116 hasAuthorship W2004564116A5077155945 @default.
• W2004564116 hasBestOaLocation W20045641161 @default.
• W2004564116 hasConcept C104317684 @default.
• W2004564116 hasConcept C127716648 @default.
• W2004564116 hasConcept C153911025 @default.
• W2004564116 hasConcept C159654299 @default.
• W2004564116 hasConcept C203014093 @default.
• W2004564116 hasConcept C2778453870 @default.
• W2004564116 hasConcept C2779528874 @default.
• W2004564116 hasConcept C36394416 @default.
• W2004564116 hasConcept C42362537 @default.
• W2004564116 hasConcept C54355233 @default.
• W2004564116 hasConcept C62478195 @default.
• W2004564116 hasConcept C86803240 @default.
• W2004564116 hasConcept C90059517 @default.
• W2004564116 hasConceptScore W2004564116C104317684 @default.
• W2004564116 hasConceptScore W2004564116C127716648 @default.
• W2004564116 hasConceptScore W2004564116C153911025 @default.
• W2004564116 hasConceptScore W2004564116C159654299 @default.
• W2004564116 hasConceptScore W2004564116C203014093 @default.
• W2004564116 hasConceptScore W2004564116C2778453870 @default.
• W2004564116 hasConceptScore W2004564116C2779528874 @default.
• W2004564116 hasConceptScore W2004564116C36394416 @default.
• W2004564116 hasConceptScore W2004564116C42362537 @default.
• W2004564116 hasConceptScore W2004564116C54355233 @default.
• W2004564116 hasConceptScore W2004564116C62478195 @default.
• W2004564116 hasConceptScore W2004564116C86803240 @default.
• W2004564116 hasConceptScore W2004564116C90059517 @default.
• W2004564116 hasIssue "2" @default.
• W2004564116 hasLocation W20045641161 @default.
• W2004564116 hasLocation W20045641162 @default.
• W2004564116 hasLocation W20045641163 @default.
• W2004564116 hasLocation W20045641164 @default.
• W2004564116 hasOpenAccess W2004564116 @default.
• W2004564116 hasPrimaryLocation W20045641161 @default.
• W2004564116 hasRelatedWork W1539823620 @default.
• W2004564116 hasRelatedWork W2004564116 @default.
• W2004564116 hasRelatedWork W2006639054 @default.
• W2004564116 hasRelatedWork W2036627768 @default.
• W2004564116 hasRelatedWork W2077370776 @default.
• W2004564116 hasRelatedWork W2088128221 @default.
• W2004564116 hasRelatedWork W2089643624 @default.
• W2004564116 hasRelatedWork W2101882212 @default.
• W2004564116 hasRelatedWork W2125070546 @default.
• W2004564116 hasRelatedWork W2312618767 @default.

• next