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- W2004615217 abstract "One of the greatest obstacles to the control of malaria has been the spread of resistance to drugs used on a large scale. This review provides an update of the current understanding of the molecular basis for antimalarial drug resistance. Parasite intrinsic resistance is just one component that determines the in vivo efficacy of a drug. Human immune responses and pharmacologic properties play important roles in determining the clinical outcome of treatment. The emergence and spread of resistance also results from an interplay of these factors. Current efforts to characterize and deter resistance to new combination therapy are also discussed." @default.
- W2004615217 created "2016-06-24" @default.
- W2004615217 creator A5026256846 @default.
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- W2004615217 date "2009-05-01" @default.
- W2004615217 modified "2023-09-26" @default.
- W2004615217 title "Resistance to Antimalarial Drugs: Molecular, Pharmacologic, and Clinical Considerations" @default.
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- W2004615217 doi "https://doi.org/10.1203/pdr.0b013e3181a0977e" @default.
- W2004615217 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2837525" @default.
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