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- W2004620063 abstract "This chapter discusses ascorbic acid in endocrine systems. Ascorbic acid is found in highest concentration in certain endocrine tissues of almost all mammals. Overviews of the chemistry of ascorbic acid and of methods for its detection are essential for understanding ascorbic acid in biological systems. Appreciation of basic ascorbate chemistry suggests functions for ascorbate in endocrine tissues. Knowledge of the difficulties with older ascorbate assays may help to explain why formulations for ascorbate function are just emerging now. The earliest physicians did not know what ascorbic acid was, but they clearly were familiar with the end results of lack of ascorbate in the diet. The first chemically stable product in the oxidation of ascorbic acid is dehydroascorbate. For a basic understanding of the dehydroascorbate/ascorbate redox pair, it is easiest to conceptualize the two species as existing under some equilibrium. The conditions of the equilibrium are influenced not only by the original concentrations of the two species but by light, pH, and possibly temperature." @default.
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- W2004620063 date "1972-12-01" @default.
- W2004620063 modified "2023-10-18" @default.
- W2004620063 title "Resolution of ascorbic, dehydroascorbic, and diketogulonic acids by anion-exchange column chromatography" @default.
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- W2004620063 doi "https://doi.org/10.1016/s0021-9673(01)94983-0" @default.
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