FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004629757> ?p ?o ?g. }

• W2004629757 endingPage "514" @default.
• W2004629757 startingPage "505" @default.
• W2004629757 abstract "Vestibular schwannomas have been traditionally managed with microsurgical removal and in recent years, stereotactic radiotherapy. However, there is a group of patients in whom a conservative management approach might represent a desirable alternative. The aim of this study was to determine the natural history and outcome following the conservative management of 72 patients with unilateral vestibular schwannomas. This is a prospective cohort review of a previously published group of patients [Clin. Otolaryngol. (2000) 25, 28–39] with unilateral vestibular schwannoma that were initially analysed at our institution in 1998 [Walsh R.M., Bath A.P., Bance M.L. et al., Clin. Otolaryngol. (2000) 25, 28]. The mean duration of follow-up was 80 months (range 52–242 months). All the patients in the study underwent serial magnetic resonance imaging (MRI) for assessment of tumour growth. Patients were deemed to have failed conservative management if there was evidence of rapid radiological tumour growth and/or increasing signs and symptoms, which necessitated active intervention. The mean tumour growth rate for the entire group at the second review was 1 mm/year (range −0.84–9.65 mm/year). The mean growth rate for cerebellopontine angle tumours (1.3 mm/year) was significantly greater than that of internal auditory canal (IAC) tumours (0 mm/year) (P = 0.005). The majority of tumours (87.14%) grew <2 mm/year. There was significant tumour growth seen in 38.9%, no or insignificant growth in 41.7%, and negative growth in 19.4%. Twenty-three patients (32%) failed conservative management at the second review. There was no difference in the outcome of these failed patients in comparison with patients who underwent primary treatment without a period of conservative management. The mean growth rate of tumours in patients that failed conservative management (3.1 mm/year) was significantly greater than that in patients who did not fail (0.2 mm/year) (P < 0.001). No factors predictive of tumour growth or failure of conservative management were identified. Hearing deterioration with pure tone averages (0.5, 1, 2, 3 kHz) and speech discrimination scores occurred irrespective of tumour growth. This prospective study further emphasizes the role of conservative management in selected cases of vestibular schwannomas. Tumours in this study confined to the IAC typically demonstrated minimal or no growth on serial MRI scanning. Regular follow-up with interval scanning is mandatory in all patients." @default.
• W2004629757 created "2016-06-24" @default.
• W2004629757 creator A5002661666 @default.
• W2004629757 creator A5019642270 @default.
• W2004629757 creator A5029612420 @default.
• W2004629757 creator A5033151746 @default.
• W2004629757 creator A5039846033 @default.
• W2004629757 creator A5057295871 @default.
• W2004629757 creator A5064415630 @default.
• W2004629757 date "2004-10-01" @default.
• W2004629757 modified "2023-10-16" @default.
• W2004629757 title "Conservative management of vestibular schwannomas - second review of a prospective longitudinal study" @default.
• W2004629757 cites W1565695910 @default.
• W2004629757 cites W1751270199 @default.
• W2004629757 cites W1964569961 @default.
• W2004629757 cites W1972272547 @default.
• W2004629757 cites W1980601983 @default.
• W2004629757 cites W1988775382 @default.
• W2004629757 cites W1992221733 @default.
• W2004629757 cites W1995411063 @default.
• W2004629757 cites W2019502188 @default.
• W2004629757 cites W2025783519 @default.
• W2004629757 cites W2038506697 @default.
• W2004629757 cites W2046241850 @default.
• W2004629757 cites W2048977508 @default.
• W2004629757 cites W2050402457 @default.
• W2004629757 cites W2051833942 @default.
• W2004629757 cites W2071436507 @default.
• W2004629757 cites W2089402892 @default.
• W2004629757 cites W2093307448 @default.
• W2004629757 cites W2093502629 @default.
• W2004629757 cites W2100732871 @default.
• W2004629757 cites W2108303548 @default.
• W2004629757 cites W2111639355 @default.
• W2004629757 cites W2113096180 @default.
• W2004629757 cites W2132908299 @default.
• W2004629757 cites W2145808611 @default.
• W2004629757 cites W2164616455 @default.
• W2004629757 cites W2166225739 @default.
• W2004629757 cites W2230317986 @default.
• W2004629757 cites W2410724137 @default.
• W2004629757 cites W2410859678 @default.
• W2004629757 cites W2468805517 @default.
• W2004629757 cites W4234588332 @default.
• W2004629757 cites W4252793238 @default.
• W2004629757 doi "https://doi.org/10.1111/j.1365-2273.2004.00852.x" @default.
• W2004629757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15373864" @default.
• W2004629757 hasPublicationYear "2004" @default.
• W2004629757 type Work @default.
• W2004629757 sameAs 2004629757 @default.
• W2004629757 citedByCount "99" @default.
• W2004629757 countsByYear W20046297572012 @default.
• W2004629757 countsByYear W20046297572013 @default.
• W2004629757 countsByYear W20046297572014 @default.
• W2004629757 countsByYear W20046297572016 @default.
• W2004629757 countsByYear W20046297572017 @default.
• W2004629757 countsByYear W20046297572018 @default.
• W2004629757 countsByYear W20046297572019 @default.
• W2004629757 countsByYear W20046297572020 @default.
• W2004629757 countsByYear W20046297572021 @default.
• W2004629757 countsByYear W20046297572022 @default.
• W2004629757 countsByYear W20046297572023 @default.
• W2004629757 crossrefType "journal-article" @default.
• W2004629757 hasAuthorship W2004629757A5002661666 @default.
• W2004629757 hasAuthorship W2004629757A5019642270 @default.
• W2004629757 hasAuthorship W2004629757A5029612420 @default.
• W2004629757 hasAuthorship W2004629757A5033151746 @default.
• W2004629757 hasAuthorship W2004629757A5039846033 @default.
• W2004629757 hasAuthorship W2004629757A5057295871 @default.
• W2004629757 hasAuthorship W2004629757A5064415630 @default.
• W2004629757 hasConcept C126322002 @default.
• W2004629757 hasConcept C126838900 @default.
• W2004629757 hasConcept C141071460 @default.
• W2004629757 hasConcept C143409427 @default.
• W2004629757 hasConcept C163276114 @default.
• W2004629757 hasConcept C188816634 @default.
• W2004629757 hasConcept C190041318 @default.
• W2004629757 hasConcept C190892606 @default.
• W2004629757 hasConcept C2780387249 @default.
• W2004629757 hasConcept C2780904754 @default.
• W2004629757 hasConcept C2781447767 @default.
• W2004629757 hasConcept C509974204 @default.
• W2004629757 hasConcept C71924100 @default.
• W2004629757 hasConcept C72563966 @default.
• W2004629757 hasConcept C86605331 @default.
• W2004629757 hasConceptScore W2004629757C126322002 @default.
• W2004629757 hasConceptScore W2004629757C126838900 @default.
• W2004629757 hasConceptScore W2004629757C141071460 @default.
• W2004629757 hasConceptScore W2004629757C143409427 @default.
• W2004629757 hasConceptScore W2004629757C163276114 @default.
• W2004629757 hasConceptScore W2004629757C188816634 @default.
• W2004629757 hasConceptScore W2004629757C190041318 @default.
• W2004629757 hasConceptScore W2004629757C190892606 @default.
• W2004629757 hasConceptScore W2004629757C2780387249 @default.
• W2004629757 hasConceptScore W2004629757C2780904754 @default.
• W2004629757 hasConceptScore W2004629757C2781447767 @default.
• W2004629757 hasConceptScore W2004629757C509974204 @default.
• W2004629757 hasConceptScore W2004629757C71924100 @default.

• next