FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004635533> ?p ?o ?g. }

• W2004635533 endingPage "975" @default.
• W2004635533 startingPage "968" @default.
• W2004635533 abstract "We have applied immunohistology and in situ hybridization to bronchial biopsies of patients with chronic obstructive pulmonary disease (COPD) to examine neutrophil recruitment and to determine neutrophil chemoattractant and CXC receptor (CXCR) 1 and CXCR2 gene expression associated with acute severe exacerbations. Cells were counted in endobronchial biopsies of (1) patients with COPD intubated for exacerbations (E-COPD; n = 15), (2) those with COPD in a stable phase of their disease (S-COPD; n = 7), and (3) nonsmoker surgical control subjects intubated for a nonrespiratory surgical procedure (n = 15). In comparison with the nonrespiratory surgical procedure and S-COPD groups, neutrophilia and gene expression for epithelial-derived neutrophil attractant-78 (CXCL5), interleukin-8 (CXCL8), CXCR1, and CXCR2 were each upregulated in the E-COPD group (p < 0.01); compared with the S-COPD group, by 97-, 6-, 6-, 3-, and 7-fold, respectively (p < 0.01). In E-COPD, there was a significant positive association between the number of neutrophils and CXCR2 mRNA–positive cells (r = 0.79; p < 0.01) but not between the number of neutrophils and CXCR1 mRNA–positive cells. At the time of sampling of the mucosa, there was no association between neutrophil number and either the length of intubation or viral infection. Thus, in COPD, in addition to CXCL8 and CXCR1, CXCL5 and CXCR2 appear to play important roles in the airway neutrophilia characteristic of severe exacerbations." @default.
• W2004635533 created "2016-06-24" @default.
• W2004635533 creator A5001978364 @default.
• W2004635533 creator A5007986401 @default.
• W2004635533 creator A5018919457 @default.
• W2004635533 creator A5019304494 @default.
• W2004635533 creator A5035253755 @default.
• W2004635533 creator A5044911914 @default.
• W2004635533 creator A5053313939 @default.
• W2004635533 date "2003-10-15" @default.
• W2004635533 modified "2023-09-26" @default.
• W2004635533 title "Biopsy Neutrophilia, Neutrophil Chemokine and Receptor Gene Expression in Severe Exacerbations of Chronic Obstructive Pulmonary Disease" @default.
• W2004635533 cites W1483257978 @default.
• W2004635533 cites W1549347261 @default.
• W2004635533 cites W1571619727 @default.
• W2004635533 cites W1628031477 @default.
• W2004635533 cites W1736073447 @default.
• W2004635533 cites W1933597658 @default.
• W2004635533 cites W1945512486 @default.
• W2004635533 cites W1970155928 @default.
• W2004635533 cites W1973742535 @default.
• W2004635533 cites W1975907534 @default.
• W2004635533 cites W1991648511 @default.
• W2004635533 cites W1996620001 @default.
• W2004635533 cites W2001980146 @default.
• W2004635533 cites W2009343792 @default.
• W2004635533 cites W2012471161 @default.
• W2004635533 cites W2019144656 @default.
• W2004635533 cites W2020585064 @default.
• W2004635533 cites W2033380992 @default.
• W2004635533 cites W2041314309 @default.
• W2004635533 cites W2041385557 @default.
• W2004635533 cites W2051810280 @default.
• W2004635533 cites W2053517795 @default.
• W2004635533 cites W2066003346 @default.
• W2004635533 cites W2073185271 @default.
• W2004635533 cites W2076036286 @default.
• W2004635533 cites W2096242114 @default.
• W2004635533 cites W2098222985 @default.
• W2004635533 cites W2098333708 @default.
• W2004635533 cites W2099507082 @default.
• W2004635533 cites W2102197472 @default.
• W2004635533 cites W2117837864 @default.
• W2004635533 cites W2118410149 @default.
• W2004635533 cites W2118462450 @default.
• W2004635533 cites W2122649795 @default.
• W2004635533 cites W2126475210 @default.
• W2004635533 cites W2138556841 @default.
• W2004635533 cites W2140775892 @default.
• W2004635533 cites W2147064547 @default.
• W2004635533 cites W2151181348 @default.
• W2004635533 cites W2156692732 @default.
• W2004635533 cites W2158351251 @default.
• W2004635533 cites W2162079120 @default.
• W2004635533 cites W2167377685 @default.
• W2004635533 cites W2168233468 @default.
• W2004635533 cites W2170247979 @default.
• W2004635533 cites W2315825786 @default.
• W2004635533 cites W2409841081 @default.
• W2004635533 cites W97158386 @default.
• W2004635533 doi "https://doi.org/10.1164/rccm.200208-794oc" @default.
• W2004635533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12857718" @default.
• W2004635533 hasPublicationYear "2003" @default.
• W2004635533 type Work @default.
• W2004635533 sameAs 2004635533 @default.
• W2004635533 citedByCount "317" @default.
• W2004635533 countsByYear W20046355332012 @default.
• W2004635533 countsByYear W20046355332013 @default.
• W2004635533 countsByYear W20046355332014 @default.
• W2004635533 countsByYear W20046355332015 @default.
• W2004635533 countsByYear W20046355332016 @default.
• W2004635533 countsByYear W20046355332017 @default.
• W2004635533 countsByYear W20046355332018 @default.
• W2004635533 countsByYear W20046355332019 @default.
• W2004635533 countsByYear W20046355332020 @default.
• W2004635533 countsByYear W20046355332021 @default.
• W2004635533 countsByYear W20046355332022 @default.
• W2004635533 countsByYear W20046355332023 @default.
• W2004635533 crossrefType "journal-article" @default.
• W2004635533 hasAuthorship W2004635533A5001978364 @default.
• W2004635533 hasAuthorship W2004635533A5007986401 @default.
• W2004635533 hasAuthorship W2004635533A5018919457 @default.
• W2004635533 hasAuthorship W2004635533A5019304494 @default.
• W2004635533 hasAuthorship W2004635533A5035253755 @default.
• W2004635533 hasAuthorship W2004635533A5044911914 @default.
• W2004635533 hasAuthorship W2004635533A5053313939 @default.
• W2004635533 hasConcept C126322002 @default.
• W2004635533 hasConcept C12823836 @default.
• W2004635533 hasConcept C13373296 @default.
• W2004635533 hasConcept C142724271 @default.
• W2004635533 hasConcept C203014093 @default.
• W2004635533 hasConcept C2776780178 @default.
• W2004635533 hasConcept C2776914184 @default.
• W2004635533 hasConcept C2777802486 @default.
• W2004635533 hasConcept C68324877 @default.
• W2004635533 hasConcept C71924100 @default.
• W2004635533 hasConcept C84913492 @default.
• W2004635533 hasConcept C90924648 @default.

• next