Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004658635> ?p ?o ?g. }
- W2004658635 endingPage "e26" @default.
- W2004658635 startingPage "e26" @default.
- W2004658635 abstract "Seminal discoveries have established the role of complex tumor microenvironment (TME) in cancer progression; and later on also uncovered that vesiculation is an integral part of intercellular communication among various cell types in coordinating the tumor assembly in a dynamic manner. Exosomes are small membrane bound endosomal vesicles, which are classically known for their role in discarding cellular wastes; however, recent reports underlined their novel role in malignancy by their release from cells into the TME. Since then, the role of exosomes have been a subject of increasing interest, as exosome mediated intercellular communications offer a novel reciprocal relationship between cancer and stromal cells within the TME and modulate the fate and function of the recipient cells to finally shape the tumor progression. Exosomes are characterised by different features including size, content and mode of delivery; and its cargo delivers interesting bioactive components in the form of proteins, miRNAs or other molecules to the target cell. In the pursuit of further study of exosomes, it was found that with the help of its distinct bioactive components, exosomes specifically regulate tumor growth, angiogenesis, metastasis as well as drug resistance properties. In fact, it acts as a bridge between different signaling networks, present inside the spatially distant cells of the heterogeneous tumor population. In the current endeavour, we have highlighted the role of exosomes in modulating the intercellular crosstalk during tumor growth and progression, and proposed certain novel roles of exosomes to address the few enigmatic questions of cancer cell biology." @default.
- W2004658635 created "2016-06-24" @default.
- W2004658635 creator A5016909200 @default.
- W2004658635 creator A5032561478 @default.
- W2004658635 creator A5041375274 @default.
- W2004658635 creator A5050707801 @default.
- W2004658635 creator A5074046866 @default.
- W2004658635 creator A5088611385 @default.
- W2004658635 date "2014-09-25" @default.
- W2004658635 modified "2023-10-14" @default.
- W2004658635 title "Exosomes: Emerging Players of Intercellular Communication in Tumor Microenvironment" @default.
- W2004658635 cites W129731631 @default.
- W2004658635 cites W1502784604 @default.
- W2004658635 cites W15114388 @default.
- W2004658635 cites W1511964634 @default.
- W2004658635 cites W1538522759 @default.
- W2004658635 cites W1555041989 @default.
- W2004658635 cites W1571387405 @default.
- W2004658635 cites W1762620449 @default.
- W2004658635 cites W1877686344 @default.
- W2004658635 cites W1893364625 @default.
- W2004658635 cites W1915536483 @default.
- W2004658635 cites W1968012290 @default.
- W2004658635 cites W1973242875 @default.
- W2004658635 cites W1973449430 @default.
- W2004658635 cites W1975301108 @default.
- W2004658635 cites W1975320047 @default.
- W2004658635 cites W1976026714 @default.
- W2004658635 cites W1977692564 @default.
- W2004658635 cites W1979751563 @default.
- W2004658635 cites W1983275829 @default.
- W2004658635 cites W1984557698 @default.
- W2004658635 cites W1987019376 @default.
- W2004658635 cites W1991390602 @default.
- W2004658635 cites W1992556034 @default.
- W2004658635 cites W1996877529 @default.
- W2004658635 cites W1996997447 @default.
- W2004658635 cites W1998802762 @default.
- W2004658635 cites W1999508205 @default.
- W2004658635 cites W2001353598 @default.
- W2004658635 cites W2001937407 @default.
- W2004658635 cites W2017669919 @default.
- W2004658635 cites W2019004412 @default.
- W2004658635 cites W2019604250 @default.
- W2004658635 cites W2019888542 @default.
- W2004658635 cites W2020404158 @default.
- W2004658635 cites W2024745748 @default.
- W2004658635 cites W2024800076 @default.
- W2004658635 cites W2027167191 @default.
- W2004658635 cites W2028445515 @default.
- W2004658635 cites W2028566550 @default.
- W2004658635 cites W2030642913 @default.
- W2004658635 cites W2038479057 @default.
- W2004658635 cites W2039313867 @default.
- W2004658635 cites W2040481506 @default.
- W2004658635 cites W2047960154 @default.
- W2004658635 cites W2053306406 @default.
- W2004658635 cites W2054077259 @default.
- W2004658635 cites W2055313665 @default.
- W2004658635 cites W2055791162 @default.
- W2004658635 cites W2056302937 @default.
- W2004658635 cites W2058361884 @default.
- W2004658635 cites W2062180415 @default.
- W2004658635 cites W2062984171 @default.
- W2004658635 cites W2063480251 @default.
- W2004658635 cites W2067871959 @default.
- W2004658635 cites W2071134774 @default.
- W2004658635 cites W2071437736 @default.
- W2004658635 cites W2072167135 @default.
- W2004658635 cites W2073918425 @default.
- W2004658635 cites W2076306819 @default.
- W2004658635 cites W2076806011 @default.
- W2004658635 cites W2084601974 @default.
- W2004658635 cites W2089081493 @default.
- W2004658635 cites W2089154872 @default.
- W2004658635 cites W2091521007 @default.
- W2004658635 cites W2093013992 @default.
- W2004658635 cites W2098364791 @default.
- W2004658635 cites W2098637032 @default.
- W2004658635 cites W2098949645 @default.
- W2004658635 cites W2102992903 @default.
- W2004658635 cites W2103872250 @default.
- W2004658635 cites W2107008239 @default.
- W2004658635 cites W2108057472 @default.
- W2004658635 cites W2110576880 @default.
- W2004658635 cites W2112995502 @default.
- W2004658635 cites W2115956819 @default.
- W2004658635 cites W2118417616 @default.
- W2004658635 cites W2119764013 @default.
- W2004658635 cites W2121354606 @default.
- W2004658635 cites W2121479969 @default.
- W2004658635 cites W2121882633 @default.
- W2004658635 cites W2123614057 @default.
- W2004658635 cites W2124104087 @default.
- W2004658635 cites W2129062330 @default.
- W2004658635 cites W2142598717 @default.
- W2004658635 cites W2142755954 @default.
- W2004658635 cites W2143839116 @default.