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- W2004673896 abstract "A simple method of evaluating distal tubular function in children would be useful because water deprivation tests are potentially dangerous and acid loading tests are unpleasant. Osmolality of an early morning urine sample is often taken as a measure of urinary concentration in children with a history of polydipsia and polyuria, and the pH of an early morning sample is used to evaluate urinary acidification in several renal and metabolic disorders. A pH of 5.4 or less is usually taken as adequate acidification1 and an osmolality of 600 mmol/kg or more as excluding clinically significant impairment of urinary concentration.2 We determined the likelihood of achieving these values in a single early morning urine sample from healthy children.We collected an early morning urine sample from 322 healthy children and adolescents (age range 3 years 11 months to 18 …" @default.
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- W2004673896 date "1996-05-25" @default.
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- W2004673896 title "Specificity of pH and osmolality of early morning urine sample in assessing distal renal tubular function in children: results in healthy children" @default.
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- W2004673896 doi "https://doi.org/10.1136/bmj.312.7042.1337" @default.
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