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- W2004676005 abstract "The role of the C8 gem-dimethyl group in the A-ring of bryostatin 1 has been examined through chemical synthesis and biological evaluation of a new analogue. Assays for biological function using U937, K562, and MV4-11 cells as well as the profiles for downregulation of PKC isozymes revealed that the presence of this group is not a critical determinant for the unique pattern of biological activity of bryostatin." @default.
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- W2004676005 date "2012-06-01" @default.
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- W2004676005 title "Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity" @default.
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- W2004676005 doi "https://doi.org/10.1016/j.bmcl.2012.04.073" @default.
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