Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004678974> ?p ?o ?g. }
- W2004678974 endingPage "498" @default.
- W2004678974 startingPage "491" @default.
- W2004678974 abstract "✓ The effectiveness of ventroposterolateral pallidotomy in the treatment of akinesia and rigidity is not a new discovery and agrees with recent investigations into the pathogenesis of Parkinson's disease, which highlight the role played by the unbridled activity of the subthalamic nucleus (STN) and the consequent overactivity of the globus pallidus internalis (GPi). Because high-frequency stimulation can reversibly incapacitate a nerve structure, we applied stimulation to the same target. Seven patients suffering from severe Parkinson's disease (Stages III–V on the Hoehn and Yahr scale) and, particularly, bradykinesia, rigidity, and levodopa-induced dyskinesias underwent unilateral electrode implantation in the posteroventral GPi. Follow-up evaluation using the regular Unified Parkinson's Disease Rating Scale has been conducted for 1 year in all seven patients, 2 years in five of them, and 3 years in one. In all cases high-frequency stimulation has alleviated akinesia and rigidity and has generally improved gait and speech disturbances. In some cases tremor was attenuated. In a similar manner, the authors observed a marked diminution in levodopa-induced dyskinesias. This could be an excellent primary therapy for younger patients exhibiting severe bradykinesia, rigidity, and levodopa-induced dyskinesias, which would allow therapists to keep ventroposterolateral pallidotomy in reserve as a second weapon." @default.
- W2004678974 created "2016-06-24" @default.
- W2004678974 creator A5001487309 @default.
- W2004678974 creator A5003099397 @default.
- W2004678974 creator A5017923995 @default.
- W2004678974 creator A5032794342 @default.
- W2004678974 creator A5044165853 @default.
- W2004678974 creator A5053782031 @default.
- W2004678974 date "1997-10-01" @default.
- W2004678974 modified "2023-09-25" @default.
- W2004678974 title "High-frequency stimulation of the globus pallidus internalis in Parkinson's disease: a study of seven cases" @default.
- W2004678974 cites W1768450208 @default.
- W2004678974 cites W1904515909 @default.
- W2004678974 cites W1982583848 @default.
- W2004678974 cites W1982827121 @default.
- W2004678974 cites W1982864501 @default.
- W2004678974 cites W1986059795 @default.
- W2004678974 cites W1990280414 @default.
- W2004678974 cites W1992786297 @default.
- W2004678974 cites W1994285435 @default.
- W2004678974 cites W1996407501 @default.
- W2004678974 cites W2012907161 @default.
- W2004678974 cites W2013102569 @default.
- W2004678974 cites W2021663147 @default.
- W2004678974 cites W2022553955 @default.
- W2004678974 cites W2031170958 @default.
- W2004678974 cites W2038449798 @default.
- W2004678974 cites W2046481771 @default.
- W2004678974 cites W2048550295 @default.
- W2004678974 cites W2050540607 @default.
- W2004678974 cites W2051101627 @default.
- W2004678974 cites W2054102932 @default.
- W2004678974 cites W2062268242 @default.
- W2004678974 cites W2062865989 @default.
- W2004678974 cites W2069305977 @default.
- W2004678974 cites W2074402500 @default.
- W2004678974 cites W2074616189 @default.
- W2004678974 cites W2080357105 @default.
- W2004678974 cites W2087565659 @default.
- W2004678974 cites W2088495343 @default.
- W2004678974 cites W2089653852 @default.
- W2004678974 cites W2136871463 @default.
- W2004678974 cites W2169134951 @default.
- W2004678974 cites W2176873872 @default.
- W2004678974 cites W34204317 @default.
- W2004678974 cites W4235634822 @default.
- W2004678974 cites W4322702676 @default.
- W2004678974 doi "https://doi.org/10.3171/jns.1997.87.4.0491" @default.
- W2004678974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9322838" @default.
- W2004678974 hasPublicationYear "1997" @default.
- W2004678974 type Work @default.
- W2004678974 sameAs 2004678974 @default.
- W2004678974 citedByCount "200" @default.
- W2004678974 countsByYear W20046789742012 @default.
- W2004678974 countsByYear W20046789742013 @default.
- W2004678974 countsByYear W20046789742014 @default.
- W2004678974 countsByYear W20046789742015 @default.
- W2004678974 countsByYear W20046789742016 @default.
- W2004678974 countsByYear W20046789742018 @default.
- W2004678974 countsByYear W20046789742019 @default.
- W2004678974 countsByYear W20046789742020 @default.
- W2004678974 countsByYear W20046789742021 @default.
- W2004678974 countsByYear W20046789742022 @default.
- W2004678974 countsByYear W20046789742023 @default.
- W2004678974 crossrefType "journal-article" @default.
- W2004678974 hasAuthorship W2004678974A5001487309 @default.
- W2004678974 hasAuthorship W2004678974A5003099397 @default.
- W2004678974 hasAuthorship W2004678974A5017923995 @default.
- W2004678974 hasAuthorship W2004678974A5032794342 @default.
- W2004678974 hasAuthorship W2004678974A5044165853 @default.
- W2004678974 hasAuthorship W2004678974A5053782031 @default.
- W2004678974 hasBestOaLocation W20046789741 @default.
- W2004678974 hasConcept C126322002 @default.
- W2004678974 hasConcept C127413603 @default.
- W2004678974 hasConcept C138496976 @default.
- W2004678974 hasConcept C15744967 @default.
- W2004678974 hasConcept C160343418 @default.
- W2004678974 hasConcept C169760540 @default.
- W2004678974 hasConcept C24998067 @default.
- W2004678974 hasConcept C2777319143 @default.
- W2004678974 hasConcept C2778187257 @default.
- W2004678974 hasConcept C2778542668 @default.
- W2004678974 hasConcept C2779134260 @default.
- W2004678974 hasConcept C2779734285 @default.
- W2004678974 hasConcept C2780278869 @default.
- W2004678974 hasConcept C2780304432 @default.
- W2004678974 hasConcept C2781083702 @default.
- W2004678974 hasConcept C529278444 @default.
- W2004678974 hasConcept C66938386 @default.
- W2004678974 hasConcept C71924100 @default.
- W2004678974 hasConcept C83849319 @default.
- W2004678974 hasConcept C99508421 @default.
- W2004678974 hasConceptScore W2004678974C126322002 @default.
- W2004678974 hasConceptScore W2004678974C127413603 @default.
- W2004678974 hasConceptScore W2004678974C138496976 @default.
- W2004678974 hasConceptScore W2004678974C15744967 @default.
- W2004678974 hasConceptScore W2004678974C160343418 @default.
- W2004678974 hasConceptScore W2004678974C169760540 @default.