Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004690990> ?p ?o ?g. }
- W2004690990 endingPage "430" @default.
- W2004690990 startingPage "416" @default.
- W2004690990 abstract "We report a large-scale comparison of sequence data from the filamentous fungus Neurospora crassa with the complete genome sequence of Saccharomyces cerevisiae. N. crassa is considerably more morphologically and developmentally complex than S. cerevisiae. We found that N. crassa has a much higher proportion of orphan genes than S. cerevisiae, suggesting that its morphological complexity reflects the acquisition or maintenance of novel genes, consistent with its larger genome. Our results also indicate the loss of specific genes from S. cerevisiae. Surprisingly, some of the genes lost from S. cerevisiae are involved in basic cellular processes, including translation and ion (especially calcium) homeostasis. Horizontal gene transfer from prokaryotes appears to have played a relatively modest role in the evolution of the N. crassa genome. Differences in the overall rate of molecular evolution between N. crassa and S. cerevisiae were not detected. Our results indicate that the current public sequence databases have fairly complete samples of gene families with ancient conserved regions, suggesting that further sequencing will not substantially change the proportion of genes with homologs among distantly related groups. Models of the evolution of fungal genomes compatible with these results, and their functional implications, are discussed." @default.
- W2004690990 created "2016-06-24" @default.
- W2004690990 creator A5018960734 @default.
- W2004690990 creator A5052511647 @default.
- W2004690990 creator A5084280512 @default.
- W2004690990 creator A5087747590 @default.
- W2004690990 date "2000-04-01" @default.
- W2004690990 modified "2023-10-18" @default.
- W2004690990 title "Large-Scale Comparison of Fungal Sequence Information: Mechanisms of Innovation in <i>Neurospora crassa</i> and Gene Loss in <i>Saccharomyces cerevisiae</i>" @default.
- W2004690990 cites W115648077 @default.
- W2004690990 cites W1513332069 @default.
- W2004690990 cites W1519987066 @default.
- W2004690990 cites W1578832578 @default.
- W2004690990 cites W1585037542 @default.
- W2004690990 cites W1598017526 @default.
- W2004690990 cites W1641544182 @default.
- W2004690990 cites W1825561271 @default.
- W2004690990 cites W1876617638 @default.
- W2004690990 cites W1965267392 @default.
- W2004690990 cites W1967897161 @default.
- W2004690990 cites W1969442520 @default.
- W2004690990 cites W1972784739 @default.
- W2004690990 cites W1976658858 @default.
- W2004690990 cites W1983504336 @default.
- W2004690990 cites W1987312402 @default.
- W2004690990 cites W1990453950 @default.
- W2004690990 cites W1993996978 @default.
- W2004690990 cites W2003442364 @default.
- W2004690990 cites W2006444758 @default.
- W2004690990 cites W2009523088 @default.
- W2004690990 cites W2015727531 @default.
- W2004690990 cites W2018913450 @default.
- W2004690990 cites W2019534744 @default.
- W2004690990 cites W2025756743 @default.
- W2004690990 cites W2029193532 @default.
- W2004690990 cites W2032018179 @default.
- W2004690990 cites W2033671191 @default.
- W2004690990 cites W2036224124 @default.
- W2004690990 cites W2036848170 @default.
- W2004690990 cites W2040461302 @default.
- W2004690990 cites W2045165720 @default.
- W2004690990 cites W2053096433 @default.
- W2004690990 cites W2054017637 @default.
- W2004690990 cites W2056485579 @default.
- W2004690990 cites W2059123697 @default.
- W2004690990 cites W2084653357 @default.
- W2004690990 cites W2105201042 @default.
- W2004690990 cites W2113699031 @default.
- W2004690990 cites W2116028865 @default.
- W2004690990 cites W2119782349 @default.
- W2004690990 cites W2120380304 @default.
- W2004690990 cites W2123172705 @default.
- W2004690990 cites W2127501111 @default.
- W2004690990 cites W2140020961 @default.
- W2004690990 cites W2146429849 @default.
- W2004690990 cites W2146476388 @default.
- W2004690990 cites W2152849929 @default.
- W2004690990 cites W2153283265 @default.
- W2004690990 cites W2158714788 @default.
- W2004690990 cites W2159266221 @default.
- W2004690990 cites W2159497035 @default.
- W2004690990 cites W2159718078 @default.
- W2004690990 cites W2170886436 @default.
- W2004690990 cites W2171809401 @default.
- W2004690990 cites W246672579 @default.
- W2004690990 cites W2517000487 @default.
- W2004690990 cites W4229487902 @default.
- W2004690990 cites W4230501579 @default.
- W2004690990 cites W4252706339 @default.
- W2004690990 doi "https://doi.org/10.1101/gr.10.4.416" @default.
- W2004690990 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10779483" @default.
- W2004690990 hasPublicationYear "2000" @default.
- W2004690990 type Work @default.
- W2004690990 sameAs 2004690990 @default.
- W2004690990 citedByCount "68" @default.
- W2004690990 countsByYear W20046909902012 @default.
- W2004690990 countsByYear W20046909902015 @default.
- W2004690990 countsByYear W20046909902017 @default.
- W2004690990 countsByYear W20046909902018 @default.
- W2004690990 countsByYear W20046909902019 @default.
- W2004690990 countsByYear W20046909902021 @default.
- W2004690990 countsByYear W20046909902022 @default.
- W2004690990 crossrefType "journal-article" @default.
- W2004690990 hasAuthorship W2004690990A5018960734 @default.
- W2004690990 hasAuthorship W2004690990A5052511647 @default.
- W2004690990 hasAuthorship W2004690990A5084280512 @default.
- W2004690990 hasAuthorship W2004690990A5087747590 @default.
- W2004690990 hasBestOaLocation W20046909901 @default.
- W2004690990 hasConcept C104317684 @default.
- W2004690990 hasConcept C141231307 @default.
- W2004690990 hasConcept C143065580 @default.
- W2004690990 hasConcept C2776739539 @default.
- W2004690990 hasConcept C2777251434 @default.
- W2004690990 hasConcept C2777576037 @default.
- W2004690990 hasConcept C54355233 @default.
- W2004690990 hasConcept C86803240 @default.
- W2004690990 hasConcept C92938381 @default.
- W2004690990 hasConceptScore W2004690990C104317684 @default.