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• W2004691558 abstract "Bisphenol A (BPA) and alkylphenols (APs) are well-known endocrine disrupting chemicals (EDCs) which may threat the next generations' health. We performed biomonitoring of these phenols in colostrums to assess risk of the phenols in breast-fed neonates. Study subjects were the lactating mothers who delivered babies within 2 weeks (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>325</mml:mn></mml:math>; 30.67<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mo>±</mml:mo></mml:mrow></mml:math>3.45 years) and their neonates (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>326</mml:mn></mml:math>; embryonic period, 39.1<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mrow><mml:mo>±</mml:mo></mml:mrow></mml:math>1.5 weeks). BPA, nonylphenol (NP), and octylphenol (OP) in colostrums were quantified with LC/MS/MS. Information for environmental exposure sources of the phenols was obtained by questionnaires. As results, median level of BPA in colostrums was 7.8 ng/mL, while most NP or OP was not detected. Regarding health risks of phenols, levels of total NP in colostrums were elevated among sick mothers with toxemia, thyroid disorders, gastritis, and so forth than health mothers (3.51<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mrow><mml:mo>±</mml:mo></mml:mrow></mml:math>4.98 versus 2.04<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mrow><mml:mo>±</mml:mo></mml:mrow></mml:math>3.71 ng/mL,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M7><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.02</mml:mn></mml:math>). Dairy products intake and detergents use were positively correlated with total BPA levels (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M8><mml:mi>P</mml:mi><mml:mi>s</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:math>). In conclusion, we estimate most neonates who are exposed to BPA rather than NP or OP via colostrums and recommend continuous biomonitoring of the phenols to clarify their suspected health risk on neonates and pregnant or gestation mothers." @default.
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• W2004691558 date "2013-01-01" @default.
• W2004691558 modified "2023-09-25" @default.
• W2004691558 title "Association between Endocrine Disrupting Phenols in Colostrums and Maternal and Infant Health" @default.
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• W2004691558 doi "https://doi.org/10.1155/2013/282381" @default.
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