Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004694282> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2004694282 endingPage "102" @default.
- W2004694282 startingPage "90" @default.
- W2004694282 abstract "ABSTRACT Antisera were raised to 1–34 hPTH-B and to 1–34 hPTH-N. In the assays utilizing antisera to 1–34 hPTH-B the relative affinity of 1–84 hPTH was correlated with the activity displayed by 1–34 hPTH-N. The activity of 13–34 hPTH-B was always higher than that of 1–12 hPTH, but both peptides displaced most of the radioiodinated 1–34 hPTH-B from the antiserum. This may be due to the fact that the 1–12 and 13–34 fragments contain a homologous sequence: 6–10 (-GIN-Leu-Met-His-AsN-) and 29–33 (-GIN-Leu-Val-His-AsN-). It was possible to develop a heterologous radioimmunoassay using anti-(1–34 hPTH-B) antiserum and [ 125 I] 1–34 hPTH-N with favourable properties: complete cross-reactivity of 1–84 hPTH and high sensitivity (< 10 −14 mol/tube). All antisera to 1–34 hPTH-N were characterized by a high reactivity towards 1–34 bPTH and a higher avidity for 1–84 hPTH than for 1–34 hPTH-B. In all assays using either antisera to 1–34 hPTH-B or antisera to 1–34 hPTH-N 19–24 hPTH-B was completely inactive. In accordance with our previous observation that position 30 in native hPTH is probably occupied by an aspartic acid residue, the present study seems to indicate that position 28 or 30 is indeed represented incorrectly by the structure of 1–34 hPTH-B." @default.
- W2004694282 created "2016-06-24" @default.
- W2004694282 creator A5012141421 @default.
- W2004694282 creator A5049912730 @default.
- W2004694282 creator A5063569465 @default.
- W2004694282 date "1979-01-01" @default.
- W2004694282 modified "2023-09-30" @default.
- W2004694282 title "PRODUCTION AND CHARACTERIZATION OF ANTISERA TO SYNTHETIC 1–34 HUMAN PARATHYROID HORMONE FRAGMENTS: POSSIBLE IMPLICATIONS FOR THE CORRECTNESS OF PROPOSED STRUCTURES" @default.
- W2004694282 doi "https://doi.org/10.1530/acta.0.0900090" @default.
- W2004694282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/760361" @default.
- W2004694282 hasPublicationYear "1979" @default.
- W2004694282 type Work @default.
- W2004694282 sameAs 2004694282 @default.
- W2004694282 citedByCount "4" @default.
- W2004694282 crossrefType "journal-article" @default.
- W2004694282 hasAuthorship W2004694282A5012141421 @default.
- W2004694282 hasAuthorship W2004694282A5049912730 @default.
- W2004694282 hasAuthorship W2004694282A5063569465 @default.
- W2004694282 hasConcept C104317684 @default.
- W2004694282 hasConcept C126322002 @default.
- W2004694282 hasConcept C134018914 @default.
- W2004694282 hasConcept C159654299 @default.
- W2004694282 hasConcept C176685330 @default.
- W2004694282 hasConcept C185592680 @default.
- W2004694282 hasConcept C203014093 @default.
- W2004694282 hasConcept C2780115692 @default.
- W2004694282 hasConcept C55493867 @default.
- W2004694282 hasConcept C71924100 @default.
- W2004694282 hasConcept C86803240 @default.
- W2004694282 hasConcept C91523082 @default.
- W2004694282 hasConceptScore W2004694282C104317684 @default.
- W2004694282 hasConceptScore W2004694282C126322002 @default.
- W2004694282 hasConceptScore W2004694282C134018914 @default.
- W2004694282 hasConceptScore W2004694282C159654299 @default.
- W2004694282 hasConceptScore W2004694282C176685330 @default.
- W2004694282 hasConceptScore W2004694282C185592680 @default.
- W2004694282 hasConceptScore W2004694282C203014093 @default.
- W2004694282 hasConceptScore W2004694282C2780115692 @default.
- W2004694282 hasConceptScore W2004694282C55493867 @default.
- W2004694282 hasConceptScore W2004694282C71924100 @default.
- W2004694282 hasConceptScore W2004694282C86803240 @default.
- W2004694282 hasConceptScore W2004694282C91523082 @default.
- W2004694282 hasIssue "1" @default.
- W2004694282 hasLocation W20046942821 @default.
- W2004694282 hasLocation W20046942822 @default.
- W2004694282 hasOpenAccess W2004694282 @default.
- W2004694282 hasPrimaryLocation W20046942821 @default.
- W2004694282 hasRelatedWork W1977043923 @default.
- W2004694282 hasRelatedWork W1982640511 @default.
- W2004694282 hasRelatedWork W1995476527 @default.
- W2004694282 hasRelatedWork W2000478699 @default.
- W2004694282 hasRelatedWork W2039843633 @default.
- W2004694282 hasRelatedWork W2043105234 @default.
- W2004694282 hasRelatedWork W2048230388 @default.
- W2004694282 hasRelatedWork W2048858255 @default.
- W2004694282 hasRelatedWork W2103730104 @default.
- W2004694282 hasRelatedWork W2159598174 @default.
- W2004694282 hasVolume "90" @default.
- W2004694282 isParatext "false" @default.
- W2004694282 isRetracted "false" @default.
- W2004694282 magId "2004694282" @default.
- W2004694282 workType "article" @default.