FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004696616> ?p ?o ?g. }

• W2004696616 endingPage "e47195" @default.
• W2004696616 startingPage "e47195" @default.
• W2004696616 abstract "The barnacle Balanus ( = Amphibalanus) amphitrite is a major marine fouling animal. Understanding the molecular mechanism of larval settlement in this species is critical for anti-fouling research. In this study, we cloned one isoform of p38 MAPK (Bar-p38 MAPK) from this species, which shares the significant characteristic of containing a TGY motif with other species such as yeast, Drosophila and humans. The activation of p38 MAPK was detected by an antibody that recognizes the conserved dual phosphorylation sites of TGY. The results showed that phospho-p38 MAPK (pp38 MAPK) was more highly expressed at the cyprid stage, particularly in aged cyprids, in comparison to other stages, including the nauplius and juvenile stages. Immunostaining showed that Bar-p38 MAPK and pp38 MAPK were mainly located at the cyprid antennules, and especially the third and fourth segments, which are responsible for substratum exploration during settlement. The expression and localization patterns of Bar-p38 MAPK suggest its involvement in larval settlement. This postulation was also supported by the larval settlement bioassay with the p38 MAPK inhibitor SB203580. Behavioral analysis by live imaging revealed that the larvae were still capable of exploring the surface of the substratum after SB203580 treatment. This shows that the effect of p38 MAPK on larval settlement might be by regulating the secretion of permanent proteinaceous substances. Furthermore, the level of pp38 MAPK dramatically decreased after full settlement, suggesting that Bar-p38 MAPK maybe plays a role in larval settlement rather than metamorphosis. Finally, we found that Bar-p38 MAPK was highly activated when larvae confronted extracts of adult barnacle containing settlement cues, whereas larvae pre-treated with SB203580 failed to respond to the crude adult extracts." @default.
• W2004696616 created "2016-06-24" @default.
• W2004696616 creator A5000166436 @default.
• W2004696616 creator A5028946657 @default.
• W2004696616 creator A5035027293 @default.
• W2004696616 creator A5046132791 @default.
• W2004696616 creator A5071859545 @default.
• W2004696616 creator A5076331384 @default.
• W2004696616 creator A5084480190 @default.
• W2004696616 date "2012-10-24" @default.
• W2004696616 modified "2023-10-10" @default.
• W2004696616 title "Evidence for the Involvement of p38 MAPK Activation in Barnacle Larval Settlement" @default.
• W2004696616 cites W1031179426 @default.
• W2004696616 cites W1965909642 @default.
• W2004696616 cites W1979381893 @default.
• W2004696616 cites W1980466777 @default.
• W2004696616 cites W1982318440 @default.
• W2004696616 cites W1997193779 @default.
• W2004696616 cites W1998809668 @default.
• W2004696616 cites W2003111286 @default.
• W2004696616 cites W2004335412 @default.
• W2004696616 cites W2005435678 @default.
• W2004696616 cites W2008116730 @default.
• W2004696616 cites W2021511409 @default.
• W2004696616 cites W2022999951 @default.
• W2004696616 cites W2024204517 @default.
• W2004696616 cites W2030196438 @default.
• W2004696616 cites W2032372665 @default.
• W2004696616 cites W2049085661 @default.
• W2004696616 cites W2057008723 @default.
• W2004696616 cites W2075121988 @default.
• W2004696616 cites W2092809755 @default.
• W2004696616 cites W2098719212 @default.
• W2004696616 cites W2112608400 @default.
• W2004696616 cites W2126409752 @default.
• W2004696616 cites W2138831814 @default.
• W2004696616 cites W2144099695 @default.
• W2004696616 cites W2399178707 @default.
• W2004696616 cites W4211258630 @default.
• W2004696616 cites W4256528999 @default.
• W2004696616 doi "https://doi.org/10.1371/journal.pone.0047195" @default.
• W2004696616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3480373" @default.
• W2004696616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23115639" @default.
• W2004696616 hasPublicationYear "2012" @default.
• W2004696616 type Work @default.
• W2004696616 sameAs 2004696616 @default.
• W2004696616 citedByCount "25" @default.
• W2004696616 countsByYear W20046966162013 @default.
• W2004696616 countsByYear W20046966162014 @default.
• W2004696616 countsByYear W20046966162015 @default.
• W2004696616 countsByYear W20046966162016 @default.
• W2004696616 countsByYear W20046966162017 @default.
• W2004696616 countsByYear W20046966162018 @default.
• W2004696616 countsByYear W20046966162020 @default.
• W2004696616 countsByYear W20046966162021 @default.
• W2004696616 countsByYear W20046966162022 @default.
• W2004696616 countsByYear W20046966162023 @default.
• W2004696616 crossrefType "journal-article" @default.
• W2004696616 hasAuthorship W2004696616A5000166436 @default.
• W2004696616 hasAuthorship W2004696616A5028946657 @default.
• W2004696616 hasAuthorship W2004696616A5035027293 @default.
• W2004696616 hasAuthorship W2004696616A5046132791 @default.
• W2004696616 hasAuthorship W2004696616A5071859545 @default.
• W2004696616 hasAuthorship W2004696616A5076331384 @default.
• W2004696616 hasAuthorship W2004696616A5084480190 @default.
• W2004696616 hasBestOaLocation W20046966161 @default.
• W2004696616 hasConcept C136397037 @default.
• W2004696616 hasConcept C136764020 @default.
• W2004696616 hasConcept C145097563 @default.
• W2004696616 hasConcept C173758957 @default.
• W2004696616 hasConcept C184235292 @default.
• W2004696616 hasConcept C18903297 @default.
• W2004696616 hasConcept C2777063073 @default.
• W2004696616 hasConcept C2778806186 @default.
• W2004696616 hasConcept C41008148 @default.
• W2004696616 hasConcept C51551487 @default.
• W2004696616 hasConcept C57074206 @default.
• W2004696616 hasConcept C86803240 @default.
• W2004696616 hasConcept C95444343 @default.
• W2004696616 hasConceptScore W2004696616C136397037 @default.
• W2004696616 hasConceptScore W2004696616C136764020 @default.
• W2004696616 hasConceptScore W2004696616C145097563 @default.
• W2004696616 hasConceptScore W2004696616C173758957 @default.
• W2004696616 hasConceptScore W2004696616C184235292 @default.
• W2004696616 hasConceptScore W2004696616C18903297 @default.
• W2004696616 hasConceptScore W2004696616C2777063073 @default.
• W2004696616 hasConceptScore W2004696616C2778806186 @default.
• W2004696616 hasConceptScore W2004696616C41008148 @default.
• W2004696616 hasConceptScore W2004696616C51551487 @default.
• W2004696616 hasConceptScore W2004696616C57074206 @default.
• W2004696616 hasConceptScore W2004696616C86803240 @default.
• W2004696616 hasConceptScore W2004696616C95444343 @default.
• W2004696616 hasIssue "10" @default.
• W2004696616 hasLocation W20046966161 @default.
• W2004696616 hasLocation W20046966162 @default.
• W2004696616 hasLocation W20046966163 @default.
• W2004696616 hasLocation W20046966164 @default.
• W2004696616 hasLocation W20046966165 @default.

• next