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- W2004701900 abstract "Non peptide inhibitors of cathepsin D, an aspartyl protease that has been implicated in many disease states including Alzheimer's disease, were prepared and evaluated. The most potent inhibitor of cathepsin D in this series was found to be (Z)-5-[[4-(4-benzoyl-3-hydroxy-2-propylphenoxy) methylphenyl]methylene]-2-thioxo-4-thiazolidinone (3f, IC50 = 210 nM)." @default.
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- W2004701900 date "1996-09-01" @default.
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- W2004701900 title "Synthesis and structure-activity relationships of benzophenones as inhibitors of cathepsin D" @default.
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- W2004701900 doi "https://doi.org/10.1016/0960-894x(96)00393-9" @default.
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