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- W2004709076 abstract "Most bacterial transcription activators function by making direct contact with RNA polymerase at target promoters. Some activators contact the carboxy-terminal domain of the RNA polymerase alpha subunit, some contact region 4 of the sigma70 subunit, whilst others interact with other contact sites. A number of activators are ambidextrous and can, apparently simultaneously, contact more than one target site on RNA polymerase. Expression from many promoters is co-dependent on two or more activators. There are several different mechanisms for coupling promoter activity to more than one activator: in one such mechanism, the different activators make independent contacts with different target sites on RNA polymerase." @default.
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- W2004709076 date "1998-04-01" @default.
- W2004709076 modified "2023-09-23" @default.
- W2004709076 title "Positive activation of gene expression" @default.
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- W2004709076 doi "https://doi.org/10.1016/s1369-5274(98)80005-2" @default.
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