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- W2004718110 abstract "Fluconazole susceptibility was tested in 100 clinical yeast isolates (65 Candida albicans, 13 C. glabrata, 8 C. tropicalis, 7 C. parapsilosis, 3 Saccharomyces cerevisiae, 1 each of C. krusei, C. lusitaniae, Cryptococcus neoformans, Rhodotorula glutinis) and two control strains (Candida krusei ATCC® 6258, C. parapsilosis ATCC® 22019) using broth microdilution (reference method), disk diffusion, Etest strips, Sensititre YeastOne, Candifast, Integral System Yeasts. Using M27-A breakpoints, isolates were classified as susceptible (81%), susceptible-dose dependent or Resistant with broth dilution. Rates of concordance with the reference method were good for Sensititre YeastOne, Etest and disc-diffusion (81.2%–94.7%) but very low for the Candifast® (3.1%) and Integral System (16.6%), which classified most susceptible isolates as resistant. Lack of standardisation (inoculum, medium composition) and non-objective interpretation schemes may be the cause of their poor performance. Sensititre YeastOne, Etest and disc-diffusion are potentially useful for fluconazole antifungal susceptibility testing of yeasts in clinical laboratories." @default.
- W2004718110 created "2016-06-24" @default.
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- W2004718110 date "2000-09-01" @default.
- W2004718110 modified "2023-10-03" @default.
- W2004718110 title "Commercial systems for fluconazole susceptibility testing of yeasts: comparison with the broth microdilution method" @default.
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- W2004718110 doi "https://doi.org/10.1016/s0732-8893(00)00174-7" @default.
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