Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004752855> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2004752855 endingPage "0" @default.
- W2004752855 startingPage "0" @default.
- W2004752855 abstract "Purpose: The Dual-focus Inhibition of Myopia Evaluation in New Zealand (DIMENZ) clinical trial tests the efficacy of myopic retinal defocus in slowing myopia progression. Methods: Dual-focus (DF) soft contact lenses have a central correction zone and peripheral zones that cause 2.00D of simultaneous myopic retinal defocus during distance and near viewing. Children (12-14 yrs, n=40, mean refractive error: - 2.70D) were fitted with a DF lens in one eye and a single vision distance (SVD) lens in the fellow eye. After 10 mo. wear, lens assignment was swapped between eyes and the lenses worn for a further 10 mo. Accommodation was measured using an open-field autorefractor. Myopia progression was monitored using cycloplegic autorefraction and partial coherence interferometry every 5 mo. Results: Visual acuity and contrast sensitivity of eyes wearing DF & SVD lenses were not different (p=0.209 & 0.157). When the DF lens was worn with either a single vision near (effective add = +2.50D) or a SVD lens in the fellow eye, children accommodated normally to a target at 40 cms. Preliminary results for 10 children after 10 mo. showed that the mean (± 1 SE) increase in myopia and axial length in eyes wearing the DF lens (-0.45 ± 0.40D & 0.08 ± 0.079mm) were significantly less (p<0.0001 & 0.00002) than in eyes wearing the SVD lens (-0.79 ± 0.41D & 0.21 ± 0.11 mm). Thus, DF lenses had a 12 mo. adjusted treatment effect of 0.40D & 0.15 mm. Conclusions: DF lenses provide normal acuity and contrast sensitivity. They do not alter accommodative response, so provide myopic retinal defocus at distance and near. Myopia progression is slowed significantly in eyes wearing DF lenses, suggesting that myopic defocus acts as an anti-myopiagenic stimulus." @default.
- W2004752855 created "2016-06-24" @default.
- W2004752855 creator A5036392936 @default.
- W2004752855 creator A5040855200 @default.
- W2004752855 date "2007-10-02" @default.
- W2004752855 modified "2023-09-25" @default.
- W2004752855 title "Optical inhibition of axial myopia progression" @default.
- W2004752855 doi "https://doi.org/10.1111/j.1600-0420.2007.01063_3112.x" @default.
- W2004752855 hasPublicationYear "2007" @default.
- W2004752855 type Work @default.
- W2004752855 sameAs 2004752855 @default.
- W2004752855 citedByCount "0" @default.
- W2004752855 crossrefType "journal-article" @default.
- W2004752855 hasAuthorship W2004752855A5036392936 @default.
- W2004752855 hasAuthorship W2004752855A5040855200 @default.
- W2004752855 hasConcept C118487528 @default.
- W2004752855 hasConcept C119767625 @default.
- W2004752855 hasConcept C120665830 @default.
- W2004752855 hasConcept C121332964 @default.
- W2004752855 hasConcept C15336307 @default.
- W2004752855 hasConcept C157660682 @default.
- W2004752855 hasConcept C2776502983 @default.
- W2004752855 hasConcept C2778257484 @default.
- W2004752855 hasConcept C2778887163 @default.
- W2004752855 hasConcept C2780827179 @default.
- W2004752855 hasConcept C2781135284 @default.
- W2004752855 hasConcept C2986805488 @default.
- W2004752855 hasConcept C71924100 @default.
- W2004752855 hasConceptScore W2004752855C118487528 @default.
- W2004752855 hasConceptScore W2004752855C119767625 @default.
- W2004752855 hasConceptScore W2004752855C120665830 @default.
- W2004752855 hasConceptScore W2004752855C121332964 @default.
- W2004752855 hasConceptScore W2004752855C15336307 @default.
- W2004752855 hasConceptScore W2004752855C157660682 @default.
- W2004752855 hasConceptScore W2004752855C2776502983 @default.
- W2004752855 hasConceptScore W2004752855C2778257484 @default.
- W2004752855 hasConceptScore W2004752855C2778887163 @default.
- W2004752855 hasConceptScore W2004752855C2780827179 @default.
- W2004752855 hasConceptScore W2004752855C2781135284 @default.
- W2004752855 hasConceptScore W2004752855C2986805488 @default.
- W2004752855 hasConceptScore W2004752855C71924100 @default.
- W2004752855 hasLocation W20047528551 @default.
- W2004752855 hasOpenAccess W2004752855 @default.
- W2004752855 hasPrimaryLocation W20047528551 @default.
- W2004752855 hasRelatedWork W2046203755 @default.
- W2004752855 hasRelatedWork W2052086899 @default.
- W2004752855 hasRelatedWork W2114150823 @default.
- W2004752855 hasRelatedWork W2249723340 @default.
- W2004752855 hasRelatedWork W2622373293 @default.
- W2004752855 hasRelatedWork W3150708210 @default.
- W2004752855 hasRelatedWork W4207005445 @default.
- W2004752855 hasRelatedWork W4220909329 @default.
- W2004752855 hasRelatedWork W8306680 @default.
- W2004752855 hasRelatedWork W1496857917 @default.
- W2004752855 hasVolume "85" @default.
- W2004752855 isParatext "false" @default.
- W2004752855 isRetracted "false" @default.
- W2004752855 magId "2004752855" @default.
- W2004752855 workType "article" @default.