FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004753379> ?p ?o ?g. }

• W2004753379 endingPage "501" @default.
• W2004753379 startingPage "495" @default.
• W2004753379 abstract "Droperidol and ondansetron prolong QT interval, a circumstance that has raised some concerns regarding the possibility of inducing torsades de pointes (TdP). However drug-induced spatial dispersion of ventricular repolarization has been shown to be the principal arrhythmogenic substrate for TdP. The aim of this study is to explore the effects of droperidol and ondansetron on the dispersion of repolarization, measured using the T peak-to-end interval (Tp-e) and Tp-e/QT and Tp-e/RR(1/2) ratios in surgical anesthetized patients.A randomized, double-blind study carried out on sixty-three adult patients without cardiac disease or factors favoring QT prolongation and undergoing non-cardiac surgery were randomly assigned to the droperidol or ondansetron group. Under propofol anesthesia, a 12-lead EKG was obtained, and 1.25mg droperidol or 4mg ondansetron was injected. Five minutes later, a new 12-lead EKG was recorded. EKG analyses were independently performed by two cardiologists blinded to the state of the traces or group allocation. QT, RR and Tp-e intervals were measured by averaging five successive beats in leadII (QT) or V5 (Tp-e). The mean value for each measurement was calculated for statistical analysis.Thirty-two patients (19 women) received droperidol, and 31 (22 women) ondansetron. Droperidol and ondansetron prolonged the QTcF interval (Fridericia formula) by 6.8 and 7.2ms (mean values) respectively, but neither droperidol nor ondansetron increased the Tp-e interval or Tp-e/QT and Tp-e/RR(1/2) ratios.At antiemetic doses, neither ondansetron (4mg) nor droperidol (1.25mg) increases the dispersion of ventricular repolarization in healthy adult patients anesthetized with propofol." @default.
• W2004753379 created "2016-06-24" @default.
• W2004753379 creator A5001765036 @default.
• W2004753379 creator A5014467901 @default.
• W2004753379 creator A5025395953 @default.
• W2004753379 creator A5041802656 @default.
• W2004753379 creator A5064867924 @default.
• W2004753379 creator A5073550741 @default.
• W2004753379 creator A5087166423 @default.
• W2004753379 date "2015-11-01" @default.
• W2004753379 modified "2023-10-02" @default.
• W2004753379 title "Efectos del droperidol y el ondansetrón en la dispersión de la repolarización ventricular: un estudio clínico aleatorizado, doble ciego en pacientes adultos anestesiados" @default.
• W2004753379 cites W1523568490 @default.
• W2004753379 cites W1955635070 @default.
• W2004753379 cites W1964278471 @default.
• W2004753379 cites W1970170641 @default.
• W2004753379 cites W1984313043 @default.
• W2004753379 cites W1988477452 @default.
• W2004753379 cites W1996972659 @default.
• W2004753379 cites W1999247227 @default.
• W2004753379 cites W2000440206 @default.
• W2004753379 cites W2000505332 @default.
• W2004753379 cites W2013495812 @default.
• W2004753379 cites W2021365069 @default.
• W2004753379 cites W2021852545 @default.
• W2004753379 cites W2050994835 @default.
• W2004753379 cites W2057613991 @default.
• W2004753379 cites W2059142008 @default.
• W2004753379 cites W2071805116 @default.
• W2004753379 cites W2078444138 @default.
• W2004753379 cites W2080397531 @default.
• W2004753379 cites W2082275497 @default.
• W2004753379 cites W2113497265 @default.
• W2004753379 cites W2119134132 @default.
• W2004753379 cites W2129100260 @default.
• W2004753379 cites W2130698931 @default.
• W2004753379 cites W2132155267 @default.
• W2004753379 cites W2149893317 @default.
• W2004753379 cites W2151240463 @default.
• W2004753379 cites W4239722874 @default.
• W2004753379 cites W4244617494 @default.
• W2004753379 doi "https://doi.org/10.1016/j.redar.2015.01.017" @default.
• W2004753379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25887095" @default.
• W2004753379 hasPublicationYear "2015" @default.
• W2004753379 type Work @default.
• W2004753379 sameAs 2004753379 @default.
• W2004753379 citedByCount "5" @default.
• W2004753379 countsByYear W20047533792016 @default.
• W2004753379 countsByYear W20047533792017 @default.
• W2004753379 countsByYear W20047533792020 @default.
• W2004753379 crossrefType "journal-article" @default.
• W2004753379 hasAuthorship W2004753379A5001765036 @default.
• W2004753379 hasAuthorship W2004753379A5014467901 @default.
• W2004753379 hasAuthorship W2004753379A5025395953 @default.
• W2004753379 hasAuthorship W2004753379A5041802656 @default.
• W2004753379 hasAuthorship W2004753379A5064867924 @default.
• W2004753379 hasAuthorship W2004753379A5073550741 @default.
• W2004753379 hasAuthorship W2004753379A5087166423 @default.
• W2004753379 hasConcept C118441451 @default.
• W2004753379 hasConcept C126322002 @default.
• W2004753379 hasConcept C164705383 @default.
• W2004753379 hasConcept C178697064 @default.
• W2004753379 hasConcept C2777170512 @default.
• W2004753379 hasConcept C2777953023 @default.
• W2004753379 hasConcept C2779425338 @default.
• W2004753379 hasConcept C2779703243 @default.
• W2004753379 hasConcept C2780486423 @default.
• W2004753379 hasConcept C2780852908 @default.
• W2004753379 hasConcept C42219234 @default.
• W2004753379 hasConcept C71924100 @default.
• W2004753379 hasConcept C84393581 @default.
• W2004753379 hasConceptScore W2004753379C118441451 @default.
• W2004753379 hasConceptScore W2004753379C126322002 @default.
• W2004753379 hasConceptScore W2004753379C164705383 @default.
• W2004753379 hasConceptScore W2004753379C178697064 @default.
• W2004753379 hasConceptScore W2004753379C2777170512 @default.
• W2004753379 hasConceptScore W2004753379C2777953023 @default.
• W2004753379 hasConceptScore W2004753379C2779425338 @default.
• W2004753379 hasConceptScore W2004753379C2779703243 @default.
• W2004753379 hasConceptScore W2004753379C2780486423 @default.
• W2004753379 hasConceptScore W2004753379C2780852908 @default.
• W2004753379 hasConceptScore W2004753379C42219234 @default.
• W2004753379 hasConceptScore W2004753379C71924100 @default.
• W2004753379 hasConceptScore W2004753379C84393581 @default.
• W2004753379 hasIssue "9" @default.
• W2004753379 hasLocation W20047533791 @default.
• W2004753379 hasLocation W20047533792 @default.
• W2004753379 hasOpenAccess W2004753379 @default.
• W2004753379 hasPrimaryLocation W20047533791 @default.
• W2004753379 hasRelatedWork W1523568490 @default.
• W2004753379 hasRelatedWork W1577822851 @default.
• W2004753379 hasRelatedWork W1578632556 @default.
• W2004753379 hasRelatedWork W1866044999 @default.
• W2004753379 hasRelatedWork W1991281239 @default.
• W2004753379 hasRelatedWork W1999247227 @default.
• W2004753379 hasRelatedWork W2000266901 @default.
• W2004753379 hasRelatedWork W2000440206 @default.
• W2004753379 hasRelatedWork W2766202495 @default.

• next