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- W2004766186 abstract "A stability-indicating reversed-phase liquid chromatography method was developed for the determination of nifedipine in raw material. The analyses were performed on a reversed-phase Phenomenex Luna® C18 column (250 mm × 4.6 mm), maintained at 40 ± 1°C. The mobile phase was composed of methanol:water (70:30; v/v) and was eluted isocratically at a 1.2 mL min−1 flow rate. The method was validated in terms of specificity, linearity, quantification limit, detection limit, accuracy, precision, and robustness. The response was linear in the range of 0.2–1.0 mg mL−1 (r2 = 0.9992). The relative standard deviation values for inter- and intra-day precision were 0.70% and 0.73%, respectively. Recoveries ranged between 97.5% to 101.6%. The method was successfully applied for the determination of nifedipine in raw material." @default.
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- W2004766186 date "2010-10-28" @default.
- W2004766186 modified "2023-10-15" @default.
- W2004766186 title "DEVELOPMENT AND VALIDATION OF A RAPID AND SIMPLE STABILITY-INDICATING LC METHOD FOR NIFEDIPINE" @default.
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- W2004766186 doi "https://doi.org/10.1080/10826076.2010.518936" @default.
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