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- W2004782972 abstract "The formation of a novel interpolyelectrolyte complex (IPEC) between basic butylated methacrylate copolymer and kappa-carrageenan was investigated and the product formed was characterized. Turbidity measurements and elemental analyses pointed to a 1:1 interaction of the repeating units. These results and FT-IR confirmed IPEC formation. Electronic microscopy images, particle size determination by image analysis and N(2) (77K) adsorption measurements were consistent with a porous material. This IPEC formed presented very good flowability and compactibility. Two maxima were observed in the swelling behaviour as a function of pH. The performance of the IPEC as a matrix for controlled release of drugs was evaluated, using ibuprofen as a model drug. Release profiles were properly represented by a mathematical model, which indicates that the system releases ibuprofen in a zero-order manner. These profiles could be controlled by conveniently modifying the proportion of the IPEC in the tablets." @default.
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- W2004782972 date "2008-09-01" @default.
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- W2004782972 title "Basic butylated methacrylate copolymer/kappa-carrageenan interpolyelectrolyte complex: Preparation, characterization and drug release behaviour" @default.
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- W2004782972 doi "https://doi.org/10.1016/j.ejpb.2008.04.017" @default.
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