Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004803217> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2004803217 endingPage "1137" @default.
- W2004803217 startingPage "1125" @default.
- W2004803217 abstract "We investigated the expression of gap junction connexins26, -32, and -43 in normal, reactive, and diseased human lymphoid tissue with single and double immunolabeling and confocal laser scanning microscopy. In all tissues, connexin43 positivity was detected in follicular dendritic cells positive for CD21 and CD35 antigens, around lymphoendothelial cells moderately positive for Factor VIII, CD31 and cathepsin-D antigens; and somewhat in vascular endothelia including high endothelial venules strongly positive for Factor VIII and CD31 antigens. The ultrastructural hallmark of gap junctions, pentalaminar structures with appropriate spacing, was found in follicular dendritic cell processes. Connexin43 was also detected between smooth muscle and stromal cells of the gut, in capsular fibroblasts, and in tonsil epithelium. Neither connexin32 nor -26 was revealed, except for connexin26 in the tonsil epithelium. In follicular dendritic cells, connexin43 co-localized closely with the desmosomal proteins desmoplakin and desmoglein, suggesting that cell adherence has a role in gap junction formation. Most connexin43 was observed in sinus lining cells of lymph nodes involved in malignancies and in follicular dendritic cells in the light zone of germinal centers where maturing but still proliferating lymphocytes are situated. In the light of their distribution, gap junctions may play a part in regulating the growth of germinal centers and in integrating activating or controlling signals in follicular dendritic and sinus lining cell networks. Because connexin43 is the connexin of stromal cells, finding it in follicular dendritic cells in consistent with the proposal that these cells originate from resident stromal cells." @default.
- W2004803217 created "2016-06-24" @default.
- W2004803217 creator A5054757986 @default.
- W2004803217 creator A5057780454 @default.
- W2004803217 date "1995-11-01" @default.
- W2004803217 modified "2023-09-26" @default.
- W2004803217 title "Immunohistological detection of gap junctions in human lymphoid tissue: connexin43 in follicular dendritic and lymphoendothelial cells." @default.
- W2004803217 doi "https://doi.org/10.1177/43.11.7560895" @default.
- W2004803217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7560895" @default.
- W2004803217 hasPublicationYear "1995" @default.
- W2004803217 type Work @default.
- W2004803217 sameAs 2004803217 @default.
- W2004803217 citedByCount "71" @default.
- W2004803217 countsByYear W20048032172012 @default.
- W2004803217 countsByYear W20048032172013 @default.
- W2004803217 countsByYear W20048032172014 @default.
- W2004803217 countsByYear W20048032172015 @default.
- W2004803217 countsByYear W20048032172018 @default.
- W2004803217 countsByYear W20048032172019 @default.
- W2004803217 countsByYear W20048032172020 @default.
- W2004803217 countsByYear W20048032172021 @default.
- W2004803217 crossrefType "journal-article" @default.
- W2004803217 hasAuthorship W2004803217A5054757986 @default.
- W2004803217 hasAuthorship W2004803217A5057780454 @default.
- W2004803217 hasBestOaLocation W20048032171 @default.
- W2004803217 hasConcept C142724271 @default.
- W2004803217 hasConcept C147483822 @default.
- W2004803217 hasConcept C159654299 @default.
- W2004803217 hasConcept C16930146 @default.
- W2004803217 hasConcept C185592680 @default.
- W2004803217 hasConcept C203014093 @default.
- W2004803217 hasConcept C204232928 @default.
- W2004803217 hasConcept C2776090121 @default.
- W2004803217 hasConcept C2777877921 @default.
- W2004803217 hasConcept C2778170410 @default.
- W2004803217 hasConcept C2778453870 @default.
- W2004803217 hasConcept C2779419017 @default.
- W2004803217 hasConcept C2780385752 @default.
- W2004803217 hasConcept C3753494 @default.
- W2004803217 hasConcept C502942594 @default.
- W2004803217 hasConcept C67662055 @default.
- W2004803217 hasConcept C71924100 @default.
- W2004803217 hasConcept C86803240 @default.
- W2004803217 hasConcept C8891405 @default.
- W2004803217 hasConcept C95444343 @default.
- W2004803217 hasConcept C96926380 @default.
- W2004803217 hasConceptScore W2004803217C142724271 @default.
- W2004803217 hasConceptScore W2004803217C147483822 @default.
- W2004803217 hasConceptScore W2004803217C159654299 @default.
- W2004803217 hasConceptScore W2004803217C16930146 @default.
- W2004803217 hasConceptScore W2004803217C185592680 @default.
- W2004803217 hasConceptScore W2004803217C203014093 @default.
- W2004803217 hasConceptScore W2004803217C204232928 @default.
- W2004803217 hasConceptScore W2004803217C2776090121 @default.
- W2004803217 hasConceptScore W2004803217C2777877921 @default.
- W2004803217 hasConceptScore W2004803217C2778170410 @default.
- W2004803217 hasConceptScore W2004803217C2778453870 @default.
- W2004803217 hasConceptScore W2004803217C2779419017 @default.
- W2004803217 hasConceptScore W2004803217C2780385752 @default.
- W2004803217 hasConceptScore W2004803217C3753494 @default.
- W2004803217 hasConceptScore W2004803217C502942594 @default.
- W2004803217 hasConceptScore W2004803217C67662055 @default.
- W2004803217 hasConceptScore W2004803217C71924100 @default.
- W2004803217 hasConceptScore W2004803217C86803240 @default.
- W2004803217 hasConceptScore W2004803217C8891405 @default.
- W2004803217 hasConceptScore W2004803217C95444343 @default.
- W2004803217 hasConceptScore W2004803217C96926380 @default.
- W2004803217 hasIssue "11" @default.
- W2004803217 hasLocation W20048032171 @default.
- W2004803217 hasLocation W20048032172 @default.
- W2004803217 hasOpenAccess W2004803217 @default.
- W2004803217 hasPrimaryLocation W20048032171 @default.
- W2004803217 hasRelatedWork W1590551246 @default.
- W2004803217 hasRelatedWork W2004803217 @default.
- W2004803217 hasRelatedWork W2061092267 @default.
- W2004803217 hasRelatedWork W2084598886 @default.
- W2004803217 hasRelatedWork W27457554 @default.
- W2004803217 hasRelatedWork W2884119078 @default.
- W2004803217 hasRelatedWork W3158301137 @default.
- W2004803217 hasRelatedWork W4236018926 @default.
- W2004803217 hasRelatedWork W619656481 @default.
- W2004803217 hasRelatedWork W89902651 @default.
- W2004803217 hasVolume "43" @default.
- W2004803217 isParatext "false" @default.
- W2004803217 isRetracted "false" @default.
- W2004803217 magId "2004803217" @default.
- W2004803217 workType "article" @default.