FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004805860> ?p ?o ?g. }

• W2004805860 endingPage "871" @default.
• W2004805860 startingPage "864" @default.
• W2004805860 abstract "Calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP), a target protein of S100, has been identified as a component of a novel ubiquitinylation complex leading to beta-catenin degradation, which was found to be related to the malignant phenotypes of gastric cancer. However, the roles of CacyBP/SIP in renal cell carcinoma still remain unclear. In the present study, we had analyzed the expression of the CacyBP/SIP protein in human renal cancer cells and clinical tissue samples. The possible roles of CacyBP/SIP in regulating the malignant phenotype of renal cancer cells were also investigated. The results demonstrated that the expression of CacyBP/SIP was markedly down-regulated in renal cell carcinoma tissues and cell lines. Ectopic overexpression of CacyBP/SIP in A498 cells inhibited the proliferation of this cell and delayed cell cycle progression significantly, which might be related to the down-regulation of Cyclin D1 through reducing beta-catenin protein. CacyBP/SIP also suppressed colony formation in soft agar and its tumorigenicity in nude mice. Taken together, our work showed that CacyBP/SIP, as a novel down-regulated gene in renal cell carcinoma, suppressed proliferation and tumorigenesis of renal cancer cells." @default.
• W2004805860 created "2016-06-24" @default.
• W2004805860 creator A5002155632 @default.
• W2004805860 creator A5004923502 @default.
• W2004805860 creator A5013881064 @default.
• W2004805860 creator A5018860616 @default.
• W2004805860 creator A5029874719 @default.
• W2004805860 creator A5033856784 @default.
• W2004805860 creator A5056755738 @default.
• W2004805860 creator A5078303906 @default.
• W2004805860 creator A5079975859 @default.
• W2004805860 creator A5089200400 @default.
• W2004805860 date "2007-05-01" @default.
• W2004805860 modified "2023-09-27" @default.
• W2004805860 title "Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma" @default.
• W2004805860 cites W122563694 @default.
• W2004805860 cites W1752089945 @default.
• W2004805860 cites W1975406254 @default.
• W2004805860 cites W1976891980 @default.
• W2004805860 cites W1981734556 @default.
• W2004805860 cites W1984177486 @default.
• W2004805860 cites W1998391510 @default.
• W2004805860 cites W2014519647 @default.
• W2004805860 cites W2015418522 @default.
• W2004805860 cites W2020634703 @default.
• W2004805860 cites W2028680729 @default.
• W2004805860 cites W2041941722 @default.
• W2004805860 cites W2046464769 @default.
• W2004805860 cites W2051070936 @default.
• W2004805860 cites W2055220901 @default.
• W2004805860 cites W2080082509 @default.
• W2004805860 cites W2082338893 @default.
• W2004805860 cites W2092542726 @default.
• W2004805860 cites W2105389477 @default.
• W2004805860 cites W2118547427 @default.
• W2004805860 cites W2129122766 @default.
• W2004805860 cites W2129256297 @default.
• W2004805860 cites W2130123676 @default.
• W2004805860 cites W2139885850 @default.
• W2004805860 cites W2146634942 @default.
• W2004805860 doi "https://doi.org/10.1016/j.bbrc.2007.03.080" @default.
• W2004805860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17400182" @default.
• W2004805860 hasPublicationYear "2007" @default.
• W2004805860 type Work @default.
• W2004805860 sameAs 2004805860 @default.
• W2004805860 citedByCount "49" @default.
• W2004805860 countsByYear W20048058602012 @default.
• W2004805860 countsByYear W20048058602013 @default.
• W2004805860 countsByYear W20048058602014 @default.
• W2004805860 countsByYear W20048058602015 @default.
• W2004805860 countsByYear W20048058602016 @default.
• W2004805860 countsByYear W20048058602017 @default.
• W2004805860 countsByYear W20048058602018 @default.
• W2004805860 countsByYear W20048058602019 @default.
• W2004805860 countsByYear W20048058602020 @default.
• W2004805860 countsByYear W20048058602021 @default.
• W2004805860 countsByYear W20048058602022 @default.
• W2004805860 countsByYear W20048058602023 @default.
• W2004805860 crossrefType "journal-article" @default.
• W2004805860 hasAuthorship W2004805860A5002155632 @default.
• W2004805860 hasAuthorship W2004805860A5004923502 @default.
• W2004805860 hasAuthorship W2004805860A5013881064 @default.
• W2004805860 hasAuthorship W2004805860A5018860616 @default.
• W2004805860 hasAuthorship W2004805860A5029874719 @default.
• W2004805860 hasAuthorship W2004805860A5033856784 @default.
• W2004805860 hasAuthorship W2004805860A5056755738 @default.
• W2004805860 hasAuthorship W2004805860A5078303906 @default.
• W2004805860 hasAuthorship W2004805860A5079975859 @default.
• W2004805860 hasAuthorship W2004805860A5089200400 @default.
• W2004805860 hasConcept C11882975 @default.
• W2004805860 hasConcept C121608353 @default.
• W2004805860 hasConcept C1491633281 @default.
• W2004805860 hasConcept C153911025 @default.
• W2004805860 hasConcept C185592680 @default.
• W2004805860 hasConcept C199835354 @default.
• W2004805860 hasConcept C29537977 @default.
• W2004805860 hasConcept C502942594 @default.
• W2004805860 hasConcept C54355233 @default.
• W2004805860 hasConcept C555283112 @default.
• W2004805860 hasConcept C62112901 @default.
• W2004805860 hasConcept C81885089 @default.
• W2004805860 hasConcept C86803240 @default.
• W2004805860 hasConcept C96232424 @default.
• W2004805860 hasConcept C97037327 @default.
• W2004805860 hasConceptScore W2004805860C11882975 @default.
• W2004805860 hasConceptScore W2004805860C121608353 @default.
• W2004805860 hasConceptScore W2004805860C1491633281 @default.
• W2004805860 hasConceptScore W2004805860C153911025 @default.
• W2004805860 hasConceptScore W2004805860C185592680 @default.
• W2004805860 hasConceptScore W2004805860C199835354 @default.
• W2004805860 hasConceptScore W2004805860C29537977 @default.
• W2004805860 hasConceptScore W2004805860C502942594 @default.
• W2004805860 hasConceptScore W2004805860C54355233 @default.
• W2004805860 hasConceptScore W2004805860C555283112 @default.
• W2004805860 hasConceptScore W2004805860C62112901 @default.
• W2004805860 hasConceptScore W2004805860C81885089 @default.
• W2004805860 hasConceptScore W2004805860C86803240 @default.
• W2004805860 hasConceptScore W2004805860C96232424 @default.

• next