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- W200484823 abstract "Between April 1984 and March 1991, 45 patients with relapsing or refractory germ-cell tumours were treated in two successive phase II trials with high-dose chemotherapy and bone marrow rescue as part of salvage treatment. Thirty-two patients received the PEC protocol (cisplatin + etoposide +cyclophosphamide). Eight patients (25%), of whom 7 were responders to conventional treatment, are continuously alive without evidence of disease. Thirteen patients were treated with CarboPEC (carboplatin+etoposide+cyclophosphamide). Four patients are alive without evidence of disease. Our results emphasise the need to clearly define the clinical status (responder or refractory) of the patients at the time of high-dose chemotherapy. A European randomised trial is in preparation in order to determine the exact role of high-dose chemotherapy in the salvage setting of non seminomatous germ-cell tumours." @default.
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- W200484823 date "1994-01-01" @default.
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- W200484823 title "Salvage Chemotherapy and Autologous Bone Marrow Transplantation: 9-Year Experience at Institut Gustave-Roussy" @default.
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- W200484823 doi "https://doi.org/10.1016/b978-0-08-042198-8.50069-8" @default.
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