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• W2004867568 abstract "Although herpesvirus saimiri-transformed T lymphocytes retain multiple normal T-cell functions, only a few changes have been described. By subtractive hybridization, we have isolated a novel cellular gene, ak155, a sequence homolog of the interleukin-10 gene. Specifically herpesvirus saimiri-transformed T cells overexpress ak155 and secrete the protein into the supernatant. In other T-cell lines and in native peripheral blood cells, but not in B cells, ak155 is transcribed at low levels. AK155 forms homodimers similarly to interleukin-10. As a lymphokine, AK155 may contribute to the transformed phenotype of human T cells after infection by herpesvirus saimiri." @default.
• W2004867568 created "2016-06-24" @default.
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• W2004867568 date "2000-04-15" @default.
• W2004867568 modified "2023-10-18" @default.
• W2004867568 title "Induction of a Novel Cellular Homolog of Interleukin-10, AK155, by Transformation of T Lymphocytes with Herpesvirus Saimiri" @default.
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• W2004867568 doi "https://doi.org/10.1128/jvi.74.8.3881-3887.2000" @default.
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