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- W2004869946 abstract "As a continuation of our study of the properties of the cis-trans platinum series we have investigated the DNA-Pt complexes of [Pt(dien)Cl]Cl, cis-Pt (en)Cl2, cis-Pt (NH3)2Cl2 and K2[PtCl4] by atomic absorption spectrophotometry. The DNA-Pt complexes correspond to the saturation of the N7-(Guanine) sites. It has been found that the chelate complexes obtained with cis-Pt(en)Cl2, cis-Pt(NH3)2Cl1 and K2[PtCl4] show the same absorbance. The [Pt(dien)Cl]Cl and trans-Pt (NH3)2Cl2 which are bound to the N7 (tuanine) site only, show an absorbance greater than the chelate complexes by a factor of two. In addition, it has been possible in the case of the trans-Pt (NH3)CCl1 complex to follow the fixation of platinum to DNA by atomic absorption spectrophotometry. The result is similar to the ionic chlorine liberation procedure reported previously." @default.
- W2004869946 created "2016-06-24" @default.
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- W2004869946 date "1976-08-01" @default.
- W2004869946 modified "2023-09-30" @default.
- W2004869946 title "Differentiation between chelated and non-chelated DNA - Pt complexes by atomic absorption spectrophotometry" @default.
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- W2004869946 doi "https://doi.org/10.1016/0005-2787(76)90484-6" @default.
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