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- W2004886523 abstract "Two plasmids containing nonoverlapping deletions of the herpes simplex virus thymidine kinase gene were introduced into thymidine kinase-deficient mouse L cells by DNA-mediated gene transfer. Thymidine kinase-producing transformants were generated by a mixture of the two plasmids at a frequency significantly greater than that generated by either plasmid alone. Southern blot analyses demonstrated that functional thymidine kinase genes were generated by homologous recombination between the two deletion mutants." @default.
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- W2004886523 date "1983-01-14" @default.
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- W2004886523 title "Recombination During Gene Transfer into Mouse Cells Can Restore the Function of Deleted Genes" @default.
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- W2004886523 doi "https://doi.org/10.1126/science.6294829" @default.
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