Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004893889> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2004893889 endingPage "1040" @default.
- W2004893889 startingPage "1035" @default.
- W2004893889 abstract "To determine if the calcium antagonist nicardipine protects the myocardium against ischemia, myocardial lactate, hypoxanthine and prostanoid function was studied in 12 patients during percutaneous transluminal coronary angioplasty (PTCA). Values were obtained before balloon inflation and during 4 minutes after deflation. Intracoronary injection of 0.2 mg of nicardipine distal to the stenosis was done randomly before the first or second inflation; the other inflation served as a control. One minute after deflation, coronary sinus flow levels were similar during the nicardipine and control procedure (161 +/- 61 vs 159 +/- 72 ml/min); lactate (-9 +/- 21% vs -17 +/- 21%, p less than 0.025) and hypoxanthine production (-107 +/- 85% vs -218 +/- 153%, p less than 0.05) were less severe after nicardipine pretreatment than after control. All patients reverted to lactate extraction 4 minutes after inflation plus nicardipine infusion, whereas lactate was still produced 4 minutes after control inflation. No significant changes in thromboxane B2 or prostacyclin levels were observed in the coronary sinus 1 minute after inflation, but higher arterial thromboxane B2 values were observed after control inflation than after inflation with nicardipine infusion (median values 169 vs 78 pg/ml, p less than 0.05). In conclusion, intracoronary infusion of nicardipine reduced signs of ischemia and alterations in prostanoid handling after coronary occlusion. The mechanisms of myocardial protection appeared unrelated to coronary sinus blood flow changes or to a systemic effect of nicardipine." @default.
- W2004893889 created "2016-06-24" @default.
- W2004893889 creator A5045343464 @default.
- W2004893889 creator A5061676012 @default.
- W2004893889 creator A5073816426 @default.
- W2004893889 creator A5088914366 @default.
- W2004893889 creator A5090625983 @default.
- W2004893889 date "1987-05-01" @default.
- W2004893889 modified "2023-09-26" @default.
- W2004893889 title "Myocardial protection by intracoronary nicardipine administration during percutaneous transluminal coronary angioplasty" @default.
- W2004893889 cites W1977421912 @default.
- W2004893889 cites W1978186638 @default.
- W2004893889 cites W1995108378 @default.
- W2004893889 cites W2009628393 @default.
- W2004893889 cites W2018601494 @default.
- W2004893889 cites W2023932912 @default.
- W2004893889 cites W2036116109 @default.
- W2004893889 cites W2037742125 @default.
- W2004893889 cites W2047218792 @default.
- W2004893889 cites W2055103382 @default.
- W2004893889 cites W2062374802 @default.
- W2004893889 cites W2084562673 @default.
- W2004893889 cites W2089180548 @default.
- W2004893889 cites W2093022081 @default.
- W2004893889 cites W2093319561 @default.
- W2004893889 cites W2152560143 @default.
- W2004893889 cites W2162805755 @default.
- W2004893889 cites W2232549179 @default.
- W2004893889 doi "https://doi.org/10.1016/0002-9149(87)90844-7" @default.
- W2004893889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2953226" @default.
- W2004893889 hasPublicationYear "1987" @default.
- W2004893889 type Work @default.
- W2004893889 sameAs 2004893889 @default.
- W2004893889 citedByCount "30" @default.
- W2004893889 countsByYear W20048938892023 @default.
- W2004893889 crossrefType "journal-article" @default.
- W2004893889 hasAuthorship W2004893889A5045343464 @default.
- W2004893889 hasAuthorship W2004893889A5061676012 @default.
- W2004893889 hasAuthorship W2004893889A5073816426 @default.
- W2004893889 hasAuthorship W2004893889A5088914366 @default.
- W2004893889 hasAuthorship W2004893889A5090625983 @default.
- W2004893889 hasConcept C126322002 @default.
- W2004893889 hasConcept C164705383 @default.
- W2004893889 hasConcept C2778043224 @default.
- W2004893889 hasConcept C2778259205 @default.
- W2004893889 hasConcept C2781128415 @default.
- W2004893889 hasConcept C42219234 @default.
- W2004893889 hasConcept C519063684 @default.
- W2004893889 hasConcept C71924100 @default.
- W2004893889 hasConceptScore W2004893889C126322002 @default.
- W2004893889 hasConceptScore W2004893889C164705383 @default.
- W2004893889 hasConceptScore W2004893889C2778043224 @default.
- W2004893889 hasConceptScore W2004893889C2778259205 @default.
- W2004893889 hasConceptScore W2004893889C2781128415 @default.
- W2004893889 hasConceptScore W2004893889C42219234 @default.
- W2004893889 hasConceptScore W2004893889C519063684 @default.
- W2004893889 hasConceptScore W2004893889C71924100 @default.
- W2004893889 hasIssue "12" @default.
- W2004893889 hasLocation W20048938891 @default.
- W2004893889 hasLocation W20048938892 @default.
- W2004893889 hasOpenAccess W2004893889 @default.
- W2004893889 hasPrimaryLocation W20048938891 @default.
- W2004893889 hasRelatedWork W2004893889 @default.
- W2004893889 hasRelatedWork W2009637534 @default.
- W2004893889 hasRelatedWork W2026031370 @default.
- W2004893889 hasRelatedWork W2073362058 @default.
- W2004893889 hasRelatedWork W2126453166 @default.
- W2004893889 hasRelatedWork W2334759169 @default.
- W2004893889 hasRelatedWork W2371910486 @default.
- W2004893889 hasRelatedWork W2439843405 @default.
- W2004893889 hasRelatedWork W2549135832 @default.
- W2004893889 hasRelatedWork W3141700921 @default.
- W2004893889 hasVolume "59" @default.
- W2004893889 isParatext "false" @default.
- W2004893889 isRetracted "false" @default.
- W2004893889 magId "2004893889" @default.
- W2004893889 workType "article" @default.