FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004967103> ?p ?o ?g. }

• W2004967103 endingPage "6577" @default.
• W2004967103 startingPage "6571" @default.
• W2004967103 abstract "Aromatase, the enzyme responsible for estrogen biosynthesis, is a particularly attractive target in the treatment of hormone-dependent breast cancer. The synthesis and biological evaluation of a series of 2-(4′-pyridylmethyl)thio, 7-alkyl- or aryl-substituted isoflavones as potential aromatase inhibitors are described. The isoflavone derivatives demonstrate IC50 values from 79 to 553 nM and compete with the endogenous substrate, androstenedione. Data supporting the ability of these analogs to suppress aromatase enzyme activity in the SK-BR-3 breast cancer cell line are also presented." @default.
• W2004967103 created "2016-06-24" @default.
• W2004967103 creator A5013532448 @default.
• W2004967103 creator A5059102143 @default.
• W2004967103 creator A5071290232 @default.
• W2004967103 creator A5076132049 @default.
• W2004967103 creator A5091303181 @default.
• W2004967103 date "2005-12-01" @default.
• W2004967103 modified "2023-10-06" @default.
• W2004967103 title "Lead optimization of 7-benzyloxy 2-(4′-pyridylmethyl)thio isoflavone aromatase inhibitors" @default.
• W2004967103 cites W1537291268 @default.
• W2004967103 cites W1972365816 @default.
• W2004967103 cites W2001779498 @default.
• W2004967103 cites W2004685736 @default.
• W2004967103 cites W2056817808 @default.
• W2004967103 cites W2079417369 @default.
• W2004967103 cites W2112850117 @default.
• W2004967103 cites W2122476299 @default.
• W2004967103 cites W2275732489 @default.
• W2004967103 cites W2604895247 @default.
• W2004967103 cites W2951542044 @default.
• W2004967103 cites W2969273703 @default.
• W2004967103 doi "https://doi.org/10.1016/j.bmc.2005.07.038" @default.
• W2004967103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16125392" @default.
• W2004967103 hasPublicationYear "2005" @default.
• W2004967103 type Work @default.
• W2004967103 sameAs 2004967103 @default.
• W2004967103 citedByCount "23" @default.
• W2004967103 countsByYear W20049671032012 @default.
• W2004967103 countsByYear W20049671032014 @default.
• W2004967103 countsByYear W20049671032015 @default.
• W2004967103 countsByYear W20049671032017 @default.
• W2004967103 countsByYear W20049671032018 @default.
• W2004967103 countsByYear W20049671032019 @default.
• W2004967103 countsByYear W20049671032023 @default.
• W2004967103 crossrefType "journal-article" @default.
• W2004967103 hasAuthorship W2004967103A5013532448 @default.
• W2004967103 hasAuthorship W2004967103A5059102143 @default.
• W2004967103 hasAuthorship W2004967103A5071290232 @default.
• W2004967103 hasAuthorship W2004967103A5076132049 @default.
• W2004967103 hasAuthorship W2004967103A5091303181 @default.
• W2004967103 hasBestOaLocation W20049671032 @default.
• W2004967103 hasConcept C111368507 @default.
• W2004967103 hasConcept C114373084 @default.
• W2004967103 hasConcept C121608353 @default.
• W2004967103 hasConcept C126322002 @default.
• W2004967103 hasConcept C127313418 @default.
• W2004967103 hasConcept C181199279 @default.
• W2004967103 hasConcept C185592680 @default.
• W2004967103 hasConcept C202751555 @default.
• W2004967103 hasConcept C2776166826 @default.
• W2004967103 hasConcept C2776683971 @default.
• W2004967103 hasConcept C2776980637 @default.
• W2004967103 hasConcept C2777164284 @default.
• W2004967103 hasConcept C2777289219 @default.
• W2004967103 hasConcept C2777911890 @default.
• W2004967103 hasConcept C2779705811 @default.
• W2004967103 hasConcept C2781253882 @default.
• W2004967103 hasConcept C530470458 @default.
• W2004967103 hasConcept C55493867 @default.
• W2004967103 hasConcept C71240020 @default.
• W2004967103 hasConcept C71315377 @default.
• W2004967103 hasConcept C71924100 @default.
• W2004967103 hasConceptScore W2004967103C111368507 @default.
• W2004967103 hasConceptScore W2004967103C114373084 @default.
• W2004967103 hasConceptScore W2004967103C121608353 @default.
• W2004967103 hasConceptScore W2004967103C126322002 @default.
• W2004967103 hasConceptScore W2004967103C127313418 @default.
• W2004967103 hasConceptScore W2004967103C181199279 @default.
• W2004967103 hasConceptScore W2004967103C185592680 @default.
• W2004967103 hasConceptScore W2004967103C202751555 @default.
• W2004967103 hasConceptScore W2004967103C2776166826 @default.
• W2004967103 hasConceptScore W2004967103C2776683971 @default.
• W2004967103 hasConceptScore W2004967103C2776980637 @default.
• W2004967103 hasConceptScore W2004967103C2777164284 @default.
• W2004967103 hasConceptScore W2004967103C2777289219 @default.
• W2004967103 hasConceptScore W2004967103C2777911890 @default.
• W2004967103 hasConceptScore W2004967103C2779705811 @default.
• W2004967103 hasConceptScore W2004967103C2781253882 @default.
• W2004967103 hasConceptScore W2004967103C530470458 @default.
• W2004967103 hasConceptScore W2004967103C55493867 @default.
• W2004967103 hasConceptScore W2004967103C71240020 @default.
• W2004967103 hasConceptScore W2004967103C71315377 @default.
• W2004967103 hasConceptScore W2004967103C71924100 @default.
• W2004967103 hasIssue "23" @default.
• W2004967103 hasLocation W20049671031 @default.
• W2004967103 hasLocation W20049671032 @default.
• W2004967103 hasLocation W20049671033 @default.
• W2004967103 hasOpenAccess W2004967103 @default.
• W2004967103 hasPrimaryLocation W20049671031 @default.
• W2004967103 hasRelatedWork W1991173835 @default.
• W2004967103 hasRelatedWork W2004967103 @default.
• W2004967103 hasRelatedWork W2014167588 @default.
• W2004967103 hasRelatedWork W2019870029 @default.
• W2004967103 hasRelatedWork W2035634962 @default.
• W2004967103 hasRelatedWork W2072566825 @default.
• W2004967103 hasRelatedWork W2132342793 @default.
• W2004967103 hasRelatedWork W2399471505 @default.

• next