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- W2004992894 abstract "In almost all multicellular organisms, cell suicide or apoptosis appears to play an important role in the maintenance of cellular homeostasis. Apoptosis is tightly regulated by a set of genes that either promote apoptosis or promote cell survival. Although a number of stimuli appear to trigger the process of apoptosis, there are two major signaling pathways of apoptosis; the death receptor pathway and the death receptor-independent or mitochondrial pathway. There is evidence to suggest that, under certain conditions and in some cell types; these two pathways may cross talk. During the past 5 years, rapid progress has been made in understanding the molecular basis of apoptosis. In this brief review, I will summarize the various molecular steps of apoptosis." @default.
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- W2004992894 date "2001-11-01" @default.
- W2004992894 modified "2023-10-04" @default.
- W2004992894 title "Molecular steps of death receptor and mitochondrial pathways of apoptosis" @default.
- W2004992894 doi "https://doi.org/10.1016/s0024-3205(01)01404-7" @default.
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