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- W2004993362 abstract "A disposible plastic (poly(methyl methacrylate)) chip containing eight open channels (375 μm in width, 300 μm in depth, 1.25 cm in length) capable of performing sequential electrospray analysis is described. The channels were constructed by simply cutting the plastic chip with a sharp knife. One end of each channel was fabricated to a sharp end, while the other was connected to a sample well. The high voltage required for electrospray was introduced into the sample solution (70% methanol/water) via a copper electrode inserted in the sample well. The solution in the sample well was continuously drawn to the sharp end of the channel by capillary action and by applying the electrospray voltage at the sample reservoir. A stable and fine Taylor cone was observed at the exit of the channel. Chemical modification on the surface of the channel was not required to decrease wettability. The octagonal plastic chip allowed sequential electrospray analyses of eight samples. The technique was also shown to be useful in rapidly determining active ingredient in a commercial tablet." @default.
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- W2004993362 date "2001-02-14" @default.
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- W2004993362 title "Sequential Electrospray Analysis Using Sharp-Tip Channels Fabricated on a Plastic Chip" @default.
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- W2004993362 doi "https://doi.org/10.1021/ac001305z" @default.
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