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- W2004993791 abstract "The purpose of this study was to examine the effect of varying oxygen tension upon microcirculatory flow. The cremaster muscle of the rat was exposed and suffused with a control Ringer's solution equilibrated with nitrogen. During this procedure the red cell velocity was measured in 10–30 μm arterioles by the dual-slit photometric method, the tissue and solution pO2 were measured with an oxygen microelectrode, and the number of flowing capillaries was determined from analysis of video tapes. For a 5-min period the suffusion solution was changed to one containing 5, 10, or 21% oxygen. As the pO2 of the suffusion solution immediately above the muscle rose from 24 to 85 mm Hg, the arteriolar red cell velocity fell from 2.36 ± 0.29 to 0.69 ± 0.30 mm/sec. The tissue pO2 averaged 19 mm Hg under the 0, 5, and 10% oxygen solutions and rose to 40 mm Hg under the 21% oxygen solution. When the solution pO2 was increased from 38 to 97 mm Hg, the capillary density fell by 48%. When the suffusion solution was equilibrated with nitrogen the tissue pO2 was 2.9 mm Hg or higher, which is above the currently accepted values for the critical pO2 in tissue." @default.
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- W2004993791 date "1976-07-01" @default.
- W2004993791 modified "2023-09-27" @default.
- W2004993791 title "The effect of oxygen on arteriolar red cell velocity and capillary density in the rat cremaster muscle" @default.
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- W2004993791 doi "https://doi.org/10.1016/0026-2862(76)90007-8" @default.
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