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- W2004999616 abstract "Mercury Methylating Microbes Mercury (Hg) most commonly becomes bioavailable and enters the food web as the organic form methylmercury, where it induces acute toxicity effects that can be magnified up the food chain. But most natural and anthropogenic Hg exists as inorganic Hg 2+ and is only transformed into methylmercury by anaerobic microorganisms—typically sulfur-reducing bacteria. Using comparative genomics, Parks et al. (p. 1332 , published online 7 February; see the Perspective by Poulain and Barkay ) identified two genes that encode a corrinoid and iron-sulfur proteins in six known Hg-methylating bacteria but were absent in nonmethylating bacteria. In two distantly related model Hg-methylating bacteria, deletion of either gene—or both genes simultaneously—reduced the ability for the bacteria to produce methylmercury but did not impair cellular growth. The presence of this two-gene cluster in several other bacterial and lineages for which genome sequences are available suggests the ability to produce methylmercury may be more broadly distributed in the microbial world than previously recognized." @default.
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- W2004999616 date "2013-03-15" @default.
- W2004999616 modified "2023-10-07" @default.
- W2004999616 title "The Genetic Basis for Bacterial Mercury Methylation" @default.
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- W2004999616 doi "https://doi.org/10.1126/science.1230667" @default.
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