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- W2005003386 abstract "1. The initial rate of l-tryptophan uptake into human red cells as a function of the concentration in the medium was studied at 25 and 37°C. 2. Uptake was resolved into saturable and linear components. Kinetic constants at 37°C were, apparent Km 1.55 mM, V 0.145 mol/l cell water per min and apparent KD 0.0103 min−1. 3. Inhibitor studies showed that l-tryptophan transport via the saturable component represents uptake by a previously unidentified transport system, designated the T-system. The linear component represents l-tryptophan transport via the L-system. 4. The substrate specificity of the T-system is apparently limited to the aromatic amino acids, l- and d-tryptophan, l-tyrosine and l-phenylalanine. The main route of l-phenylalanine transport is, however, via the L-system. l-Tyrosine is partly transported via the T-system, partly via the L-system." @default.
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- W2005003386 date "1980-05-01" @default.
- W2005003386 modified "2023-10-16" @default.
- W2005003386 title "l-Tryptophan transport in human red blood cells" @default.
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- W2005003386 doi "https://doi.org/10.1016/0005-2736(80)90015-2" @default.
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