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- W2005004102 abstract "Submitochondrial particles (SMP) from rabbit skeletal muscle mitochondria (RMM) show an energy-linked efflux of H+ in the suspending medium with either succinate or L-3-glycerolphosphate as substrates. Uncoupler not only reverses the energy-linked H+ efflux, but also induces a non-energy-linked H+ uptake. Intact RMM also show energy-linked H+ efflux under the same conditions used to energize SMP. Skeletal muscle SMP are open membrane fragments incapable of sustaining a transmembrane gradient, in contrast to SMP from beef heart, which may be closed vesicles and which show energy-linked H+ uptake. The difference of direction in energy-linked H+ movements in the two types of SMP, both of which retain the capacity for energy coupling, strongly supports the concept that this H+ movement is secondary to the energy conservation process, which is postulated to occur in the membrane and to be shielded from the suspending medium." @default.
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- W2005004102 date "1979-04-01" @default.
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- W2005004102 title "Energy-linked H+ efflux and uncoupler-induced H+ influx in submitochondrial particles from skeletal muscle" @default.
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- W2005004102 doi "https://doi.org/10.1016/s0006-291x(79)80015-7" @default.
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